Quantitative Computed Tomography
Quantitative Computed Tomography
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DOI：
10.1016/j.rcl.2010.03.001
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发表时间：
2010-05-01
影响因子：
1.9
通讯作者：
Lang, Thomas F.
中科院分区：
文献类型：
--
作者：
Lang, Thomas F.
与双x线吸收仪、高分辨率CT扫描和MR成像技术不同，由于辐射剂量和信噪比的考虑，这些技术在很大程度上局限于外周骨骼，体积定量测量提供了皮质和小梁体积骨矿物质密度的测量，横截面几何形状，以及基于患者特定有限元模型的全骨强度估计。本文主要介绍体积定量方法在骨质疏松症相关的衰老、废用和药物治疗研究中的应用。
Unlike dual x-ray absorptiometry and high-resolution CT scan and MR imaging techniques, which are largely restricted to the peripheral skeleton owing to radiation dose and signal-to-noise considerations, volumetric quantitative measures provide measures of cortical and trabecular volumetric bone mineral density, cross-sectional geometry, and estimates of whole-bone strength based on patient specific finite element modeling. This article focuses on the application of volumetric quantitative measures to studies of aging, disuse, and drug treatment as related to osteoporosis.