Daytime testing after laboratory or home-based polysomnography: comparisons of middle-aged insomnia sufferers and normal sleepers
Daytime testing after laboratory or home-based polysomnography: comparisons of middle-aged insomnia sufferers and normal sleepers
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DOI：
10.1046/j.1365-2869.2003.00335.x
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发表时间：
2003-03-01
影响因子：
4.4
通讯作者：
Meeks, G
中科院分区：
文献类型：
--
作者：
Edinger, JD;Glenn, DM;Meeks, G
许多研究表明，失眠症患者和相匹配的无抱怨的正常对照组在白天嗜睡和白天表现方面只有适度的差异。目前的研究是为了确定这种白天的比较是否会受到研究参与者在这种测试前的晚上睡觉的环境（家庭与睡眠实验室）的影响。该研究使用了一种平衡的匹配组设计，其中参与者在进行日间多次睡眠潜伏期测试（MPEST）和计算机管理的性能测试之前，在睡眠实验室或家中进行了三次连续的夜间多导睡眠图（PSG）。研究参与者为35名（18名女性和17名男性）中年（40-59岁）无抱怨的正常睡眠者和33名中年失眠患者（17名女性和16名男性），他们符合持续性原发性失眠的结构化访谈标准。分层线性统计模型的使用表明，只有接受夜间家庭PSG的失眠患者在睡眠时比接受实验室PSG的正常睡眠者更警觉。然而，这些失眠症患者在选定的反应时间测试中表现出更大的注意力丧失倾向，而不是两个正常对照组（即那些睡在实验室或那些睡在家里的人）。结果表明，夜间睡眠环境（家庭与实验室）可能会影响失眠患者和正常睡眠者随后的Mesp和性能测试比较。
Many studies have shown only modest differences between insomnia sufferers and matched, non-complaining normal controls in regard to their levels of daytime sleepiness and diurnal performances. The current study was conducted to determine whether such daytime comparisons might be affected by the setting (home vs. sleep lab) in which study participants sleep on the nights before such testing. The study used a counter-balanced, matched-group design in which participants underwent three consecutive nocturnal polysomnographs (PSG) conducted either in the sleep lab or in their homes prior to undergoing daytime multiple sleep latency test (MSLT) and computer-administered performance testing. The study participants were 35 (18 women and 17 men) middle-aged (40-59 years) non-complaining normal sleepers and 33 middle-aged insomnia sufferers (17 women and 16 men) who met structured interview criteria for persistent primary insomnia. Use of a hierarchical linear statistical model showed only insomnia sufferers who underwent nocturnal home PSG were more alert on the MSLT than were normal sleepers who underwent lab PSG. However, these insomnia sufferers showed a greater propensity toward attention lapses on selected reaction time tests than did either of the two normal control groups (i.e. either those who slept in the lab or those who slept at home). The results suggest the nocturnal sleep setting (home vs. lab) may affect subsequent MSLT and performance test comparisons of insomnia sufferers and normal sleepers.