TRANSIENT-RESPONSE IN A SOMATIC SHUNT CABLE MODEL FOR SYNAPTIC INPUT ACTIVATED AT THE TERMINAL

TRANSIENT-RESPONSE IN A SOMATIC SHUNT CABLE MODEL FOR SYNAPTIC INPUT ACTIVATED AT THE TERMINAL
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DOI:
10.1016/s0022-5193(87)80159-5
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发表时间:
1987-07-07
影响因子:
2
通讯作者:
POZNANSKI, RR
POZNANSKI, RR
中科院分区:
生物学4区
文献类型:
--
作者:
POZNANSKI, RR

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本文推广了Rall‘’-S神经元模型,将非均匀时间常数与突触输入模拟为电导的平方阶跃,得到了电紧张性电位的级数解析解.得到的主要结论是,较低的躯体时间常数减弱了位于初始极化神经元树突电缆远端的突触所引起的胞体电位的幅度.
Rall''s neuron model is extended by including a non-uniform time constant together with synaptic input modeled as a square step of conductance. An analytic solution (in series form) for the electrotonic potential is obtained. The major conclusion reached is that a lower somatic time constant attenuates the amplitude of the potential at the soma, brought about by the activation of a synapse located at the distal end of the dendritic cable in an initially polarized neuron.