An epidemiological study of urban and rural children in Pakistan: examining the relationship between delayed psychomotor development, low birth weight and postnatal growth failure.
An epidemiological study of urban and rural children in Pakistan: examining the relationship between delayed psychomotor development, low birth weight and postnatal growth failure.
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巴基斯坦城乡儿童流行病学研究：考察精神运动发育迟缓、低出生体重和产后生长障碍之间的关系。
DOI：
10.1093/trstmh/tru162
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发表时间：
2015
影响因子：
2.2
通讯作者：
Kirkwood,BettyR
中科院分区：
文献类型：
--
作者：
Avan,BilalI;Raza,SyedA;Kirkwood,BettyR
背景低出生体重与出生后生长障碍有关。目前还不能确定这两种情况是心理发展的决定因素。该研究调查是否低出生体重导致延迟的儿童心理发展，以及是否可以减轻足够的产后growth.MethodsA横断面研究进行了2002年在15个农村和11个城市社区的信德省，巴基斯坦。对1234名3岁以下儿童进行评估，包括贝利婴儿发育量表II、社会经济问卷和人体测量;采用WHO标准计算年龄别身高、身高别体重和年龄别体重的z评分。基本的研究假设进行了测试，通过多元回归modeling.ResultsOut的1219名儿童，283（23.2%）有延迟的心理发展和639（52.4%）根据人体测量失败的综合指数营养不良。在发育迟缓和体重不足之间检测到与心理发展指数的强负相关，对发育迟缓的影响幅度更大（p<0.001）。即使分析仅限于非营养不良的儿童，这种强有力的关系仍然存在。精神指数增加了2.07点，每一个单位的身高年龄z-score.ConclusionsThe低出生体重和精神发育之间的关系似乎是介导的产后生长和营养状况。这种关联表明，在营养不良的儿童中，很可能有一个群体发育迟缓。必须在针对贫困儿童的方案中强调发展需要。
BackgroundLow birth weight is known to be associated with postnatal growth failure. It is not yet established that both conditions are determinants of psychomotor development. The study investigated whether or not low birth weight leads to delayed psychomotor development of a child, and whether it can be mitigated by adequate postnatal growth.MethodsA cross-sectional study was conducted in 2002 in 15 rural and 11 urban communities of Sindh province, Pakistan. Assessment of 1234 children less than 3 years of age included Bayley's Scale of Infant Development II, socioeconomic questionnaire and anthropometry; WHO standards were used to calculate z-scores of height-for-age, weight-for-height and weight-for-age. The underlying study hypotheses were tested through multiple regression modelling.ResultsOut of 1219 children, 283 (23.2%) had delayed psychomotor development and 639 (52.4%) were undernourished according to the composite index of anthropometric failure. Strong negative associations with the psychomotor development index were detected between stunting and being underweight, with a larger magnitude of effect for stunting (p<0.001). The strong relationship persisted even when the analysis was restricted to non-malnourished children. The psychomotor index increased by 2.07 points with every unit increase in height-for-age z-score.ConclusionsThe relationship between low birth weight and psychomotor development appears to be mediated largely by postnatal growth and nutritional status. This association suggests that among undernourished children there is significant likelihood of a group that is developmentally delayed. It is important to emphasize developmental needs in programmes that target underprivileged children.