A predicted dimer-based polymorph of 10,11-dihydrocarbamazepine (Form IV)
A predicted dimer-based polymorph of 10,11-dihydrocarbamazepine (Form IV)
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DOI：
10.1039/b914365c
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发表时间：
2010
期刊：
影响因子：
3.1
通讯作者：
Jean-Baptiste Arlin;Andrea Johnston;Gary J. Miller;A. Kennedy;S. Price;A. Florence
中科院分区：
文献类型：
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作者：
Jean-Baptiste Arlin;Andrea Johnston;Gary J. Miller;A. Kennedy;S. Price;A. Florence
从气相中获得了一种新的10，11-二氢卡马西平多晶型物（IV型），它被预测为在药理学上是可行的，并显示出与I-III型中的链体基序相反的R22（8）氢键二聚体基序。
A novel polymorph of 10,11-dihydrocarbamazepine (form IV), which had been predicted to be thermodynamically feasible, was obtained from the vapour phase and displays an R22(8) hydrogen bonded dimer motif in contrast to the catemeric motifs in forms I–III.