Masked type I wheat allergy. Relation to exercise-induced anaphylaxis.
Masked type I wheat allergy. Relation to exercise-induced anaphylaxis.
复制标题
蒙面I型小麦过敏。
作者：
H. Kushimoto;T. Aoki
6例患者对小麦有I型超敏反应。3例为运动性小麦过敏反应，1例为运动性小麦荨麻疹反应（伴血管性水肿），其余2例为运动性小麦荨麻疹反应。从饮食中消除小麦完全清除了这些症状。通过简单的提取和酶消化从小麦、面筋、麦醇溶蛋白和麦谷蛋白制备过敏原，并将这些制备物用于皮肤试验。通过胃蛋白酶消化从谷蛋白、麦醇溶蛋白和谷蛋白中获得的过敏原与通过简单提取获得的小麦和谷蛋白过敏原在性质上不同，并且与运动诱导的过敏反应更相关。胰蛋白酶消化没有这种效果，消除所有这些过敏原。这些结果表明，小麦过敏原在胃中得到加强，在空肠中被破坏。
Six patients had type I hypersensitivity to wheat. Three cases were exercise-induced anaphylaxis to wheat, one was exercise-induced urticarial reaction to wheat (with angioedema), and the remaining two were exercise-accentuated urticarial reaction to wheat. Elimination of wheat from the diet completely cleared these symptoms. Allergens were prepared from wheat, gluten, gliadin, and glutenin by simple extraction and enzyme digestion, and these preparations were used in skin tests. The allergens obtained from gluten, gliadin, and glutenin by pepsin digestion were qualitatively different from wheat and gluten allergens obtained by simple extraction and were more related to exercise-induced anaphylaxis. Trypsin digestion showed no such effect and abolished all these allergens. These results indicate that wheat allergens are reinforced in the stomach and destroyed in the jejunum.
运动引起的过敏反应是胆碱能荨麻疹的表现。
DOI：
10.1016/0091-6749(81)90158-5
发表时间：
1981
期刊：
The Journal of allergy and clinical immunology
影响因子：
--
作者：
Kaplan,AP;Natbony,SF;Tawil,AP;Fruchter,L;Foster,M
通讯作者：
Foster,M