Synthesis of Novel StructurallySimplified Estrogen Analogues with Electron-Donating Groups in RingA
Synthesis of Novel StructurallySimplified Estrogen Analogues with Electron-Donating Groups in RingA
复制标题
环A中带有给电子基团的新型结构简化雌激素类似物的合成
DOI：
10.1055/s-0029-1216810
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发表时间：
2009
期刊：
影响因子：
--
通讯作者：
Linda Nacke
中科院分区：
文献类型：
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作者：
L. Tietze;Carsten A. Vock;Ilga K Krimmelbein;Linda Nacke
通过溴化、甲酰化、Corey-Fuchs 反应、消除和 Sonogashira 反应，通过五到八个步骤从大多数市售取代苯甲醚制备了 25 种新型雌激素类似物库。
A library of 25 novel estrogen analogues were prepared in five to eight steps from mostly commercially available substituted anisoles via bromination, formylation, Corey―Fuchs reaction, elimination, and Sonogashira reaction.