Sequential information of self-produced song is represented in the auditory areas in male Bengalese finches
Sequential information of self-produced song is represented in the auditory areas in male Bengalese finches
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DOI：
10.1097/wnr.0b013e32835375ef
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发表时间：
2012-05-30
期刊：
影响因子：
1.7
通讯作者：
Okanoya, Kazuo
中科院分区：
文献类型：
--
作者：
Kato, Yoko;Kato, Masaki;Okanoya, Kazuo
雄性孟加拉雀有一个复杂的歌曲序列模式，包含多种元素。学习和创作歌曲需要记住音韵和元素的顺序。我们测试了雄性雀对自己歌声的听觉记忆，以确定听觉记忆是否包括元素的顺序。立即早期基因ZENK是由听觉处理诱导的，在第二听觉区的尾内侧巢皮层（NCM）和尾内侧中皮层（CMM）响应于歌曲呈现。重复呈现同一首歌曲会导致这些区域的ZENK表达减少，反映出对听觉处理的习惯化。我们使用习惯化-disabituation方法研究了听觉处理的顺序差异。在反复呈现雄雀自己的歌声刺激后，我们将刺激改变为一系列杂乱的歌声。如果混洗歌曲诱导ZENK表达，则表明听觉区域已被顺序差异破坏。与同种新歌和同一首歌的表达相比，洗牌歌曲导致NCM中的ZENK表达处于中间状态。中间表达的趋势是类似的CMM，但是，一个显着的差异之间观察到同种歌曲和洗牌的歌曲。这些结果表明，顺序差异造成了部分disabituation在NCM。因此，听觉区不仅处理语音，而且还处理歌曲的序列。NeuroReport 23：488-492（C）2012年威科健康垂直酒吧Lippincott威廉姆斯&威尔金斯。
Male Bengalese finches have a complex song-sequence pattern containing multiple elements. Learning and producing songs require memorization of the phonology and the sequence of elements. We tested the auditory memory of male finches for their own songs to determine whether the auditory memory included the sequence of elements. An immediate early gene ZENK is induced by auditory processing in the secondary auditory area of the caudomedial nidopallium (NCM) and the caudomedial mesopallium (CMM) in response to song presentations. Repeated presentations of the same song result in a decrease in ZENK expression in these areas, reflecting habituation to auditory processing. We examined sequential differences in auditory processing using the habituation-dishabituation method. After repeatedly presenting the male finches' own song stimulus, we changed the stimulus to a shuffled sequence of songs. If the shuffled songs induced ZENK expression, it indicated that the auditory areas had been dishabituated by the sequential differences. The shuffled songs caused intermediate ZENK expression in the NCM when compared with the expression by a conspecific new song and that by the same song. The tendency toward intermediate expression was similar in the CMM; however, a significant difference was observed between the conspecific song and shuffled songs. These results suggest that the sequential difference caused a partial dishabituation in the NCM. Thus, the auditory areas processed not only the phonology but also the sequence of songs. NeuroReport 23:488-492 (C) 2012 Wolters Kluwer Health vertical bar Lippincott Williams & Wilkins.