Bone defect repair on the alveolar wall of the maxillary sinus using collagen membranes and temporal fascia: an experimental study in monkeys.
Bone defect repair on the alveolar wall of the maxillary sinus using collagen membranes and temporal fascia: an experimental study in monkeys.
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DOI：
10.1590/s1808-86942011000400006
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发表时间：
2011-07
影响因子：
2.2
通讯作者：
Anselmo Lima, Wilma Terezinha
中科院分区：
文献类型：
--
作者：
Silva, Adalberto Novaes;de Oliveira, Jose Americo;Jamur, Maria Celia;Gualberto Junqueira, Jose Ari;Correa, Vani Maria;Anselmo Lima, Wilma Terezinha
引导骨再生治疗上颌窦缺损的研究很少。应用Gen-derm - Genius Baumer、Pro-tape - Proline胶原膜和自体颞筋膜对猴上颌窦与窦腔连通的牙槽壁手术缺损进行骨修复。在这项前瞻性和实验性研究中，对4只丛尾卷尾猴（Cebus apella）进行了口鼻交流，并在180天后进行了组织学分析。在没有覆盖的缺陷（对照）中，两只动物以骨增生为主，另外两只动物以纤维结缔组织为主。在颞筋膜瓣修复的缺损中，3只动物以纤维结缔组织为主，1只动物以骨增生为主。在Gen-derm或Pro-tape胶原膜修复的缺损中，3只动物的骨增生完全，1只动物的纤维结缔组织完整。所有研究组的骨组织和纤维结缔组织均可修复手术缺损；胶原膜在骨修复过程中比颞筋膜或缺乏屏障更有益。
Few studies has been done using guided bone regeneration in maxillary sinus defects. To assess the bone repair process in surgical defects on the alveolar wall of the monkey maxillary sinus, which communicates with the sinus cavity, by using collagen membranes: Gen-derm - Genius Baumer, Pro-tape - Proline and autologous temporal fascia. In this prospective and experimental study, orosinusal communications were performed in four tufted capuchin monkeys (Cebus apella) and histologic analysis was carried out 180 days after. In the defects without a cover (control), bone proliferation predominated in two animals and fibrous connective tissue predominated in the other two. In defects repaired with a temporal fascia flap, fibrous connective tissue predominated in three animals and bone proliferation predominated in one. In the defects repaired with Gen-derm or Pro-tape collagen membranes there was complete bone proliferation in three animals and fibrous connective tissue in one. Surgical defect can be repaired with both bone tissue and fibrous connective tissue in all study groups; collagen membranes was more beneficial in the bone repair process than temporal fascia or absence of a barrier.