The epidemiology and economics of chronic obstructive pulmonary disease.
The epidemiology and economics of chronic obstructive pulmonary disease.
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DOI：
10.1513/pats.200701-001fm
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发表时间：
2007-10-01
期刊：
影响因子：
--
通讯作者：
Braman, Sidney
中科院分区：
文献类型：
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作者：
Mannino, David M;Braman, Sidney
慢性阻塞性肺疾病（COPD）是一种可预防和可治疗的疾病，在世界各地造成巨大的人类和经济负担。在发达国家，吸烟是COPD的主要危险因素，尽管其他重要的危险因素包括职业暴露、空气污染、气道高反应性、哮喘和遗传易感性。在世界大部分地区，COPD的患病率和死亡率随着吸烟的增加而持续上升，特别是女性和青少年。COPD也是残疾的重要原因，并且与共病疾病有关，例如抑郁症和心血管疾病，这增加了与这种疾病相关的巨大经济负担。更好的公共卫生和医疗干预措施，针对COPD的风险因素，并期待早期干预，可能会减少COPD对公共卫生日益增长的影响。
Chronic obstructive pulmonary disease (COPD) is a preventable and treatable disease responsible for a large human and economic burden around the world. Cigarette smoking is the main risk factor for COPD in the developed world, although other important risk factors include occupational exposures, air pollution, airway hyperresponsiveness, asthma, and genetic predisposition. In most of the world, COPD prevalence and mortality continue to rise in response to increases in smoking, particularly by women and adolescents. COPD is also an important cause of disability, and is linked to comorbid diseases, such as depression and cardiovascular disease, which adds to the large economic burden associated with this disorder. Better public health and medical interventions that target both the risk factors for COPD and look toward earlier intervention may decrease the growing public health impact of COPD.