Ornithine decarboxylase activity in lymphoid tissues of rats: effects of glucocorticoids.
Ornithine decarboxylase activity in lymphoid tissues of rats: effects of glucocorticoids.
复制标题
大鼠淋巴组织中的鸟氨酸脱羧酶活性：糖皮质激素的作用。
DOI：
10.1016/0024-3205(78)90590-8
复制
发表时间：
1978
期刊：
影响因子：
6.1
通讯作者：
J. Richards
中科院分区：
文献类型：
--
作者：
J. Richards
鸟氨酸脱羧酶的活性测定在几个组织的年轻雌性大鼠用醋酸可的松或地塞米松治疗后。在肝脏和肾脏中观察到的预期活性增加与在胸腺和脾脏中观察到的显著降低形成鲜明对比。在用地塞米松或可的松处理后5小时，胸腺中最初的高活性降低到非常低的水平，有时低于测定程序的限度。也有一个很大的下降，在酶的活性在脾脏中的酶治疗大鼠。在这两种组织中，治疗后12小时仍有明显效果。
The activity of ornithine decarboxylase was measured in several tissues of young female rats after treatment with cortisone acetate or dexamethasone. The expected increase in activity observed in liver and kidney was in marked contrast to the profound decrease found in thymus and spleen. Initially high activity in thymus was decreased to very low levels, sometimes below the limit of the assay procedure, 5 hours after treatment with dexamethasone or cortisone. There was also a large decrease in activity of the enzyme in spleen of hormone-treated rats. In both tissues, the marked effect was still evident 12 hours after treatment.