A RETROSPECTIVE REVIEW OF CASES OF ANAEROBIC EMPYEMA AND UPDATE OF BACTERIOLOGY
A RETROSPECTIVE REVIEW OF CASES OF ANAEROBIC EMPYEMA AND UPDATE OF BACTERIOLOGY
复制标题
DOI：
10.1093/clinids/20.supplement_2.s224
复制
发表时间：
1995-06-01
影响因子：
11.8
通讯作者：
FINEGOLD, SM
中科院分区：
文献类型：
--
作者：
CIVEN, R;JOUSIMIESSOMER, H;FINEGOLD, SM
我们进行了一项回顾性研究，以更新最初于1976年至1993年在沃兹沃斯厌氧细菌学临床研究实验室（洛杉矶）研究的46例厌氧性脓胸的细菌学，对所有46份胸腔液标本完成了厌氧细菌学研究，对其中41份标本完成了需氧细菌学研究。共有37份临床图表可供审查，共回收了161株厌氧分离株（每例患者3.5株），代表64个种属或类群，最常见的分离株如下：具核梭杆菌（19株）;口颊普雷沃菌群（13株，其中9株为口普雷沃菌）;脆弱拟杆菌群（11株，其中4株为B）。fragilis）;着色普雷沃氏菌属物种（17种，其中8种在中间变黑普雷沃氏菌组中）;消化链霉菌属物种（17种，其中9种是微小消化链霉菌）;真杆菌属物种（7种）;乳杆菌属物种（8种）;放线菌属物种（7种）;和梭菌属物种（7种）。其中19例为单纯厌氧菌，其中8例由单一微生物引起：F。有核细胞（5例）; B.脆弱型（2例）;在45株需氧菌中（每例患者1.1株），草绿色链球菌最常见（21株），其次是D组非肠球菌链球菌（4株）。只有9个革兰氏阴性杆菌用螺旋梯度法检测64株分离菌对青霉素的敏感性;其中21株（33%）β-内酰胺酶阳性（β-内酰胺酶阴性菌株的MIC范围为1.1至大于或等于54 μ g/mL，小于或等于0.27 μ g/mL）。
We conducted a retrospective study to update the bacteriology of 46 cases of anaerobic empyema that were originally studied between 1976 and 1993 at the Wadsworth Anaerobic Bacteriology Clinical Research Laboratory (Los Angeles), Anaerobic bacteriologic studies were completed for all 46 pleural fluid specimens, and aerobic bacteriologic studies were completed for 41 of these specimens. Thirty-seven clinical charts were available for review, A total of 161 anaerobic isolates (3.5 per patient) representing 64 species or groups were recovered, The most common isolates were as follows: Fusobacterium nucleatum (19); Prevotella oris-buccae group (13, 9 of which were P. oris); Bacteroides fragilis group (11, 4 of which were B. fragilis); pigmented Prevotella species (17, 8 of which were in the Prevotella intermedia-nigrescens group); Peptostreptococcus species (17, 9 of which were Peptostreptococcus micros); Eubacterium species (7); Lactobacillus species (8); Actinomyces species (7); and Clostridium species (7). Nineteen of the cases were of purely anaerobic etiology; of these, eight were caused by a single organism: F. nucleatum (five cases); B. fragilis (two cases); and Prevotella magnus (one case), Of the 45 aerobic isolates (1,1 per patient), viridans streptococci were most common (21 isolates), followed by group D nonenterococcal streptococci (four isolates). Only nine gram-negative rods (six enteric and three nonenteric organisms) and one Staphylococcus aureus isolate were recovered, The susceptibility to penicillin of 64 isolates was examined with use of the spiral gradient method; 21 (33%) of these isolates were beta-lactamase positive (MICs ranged from 1.1 to greater than or equal to 54 mu g/mL vs. less than or equal to 0.27 mu g/mL for beta-lactamase-negative strains).