Cerebral Lateralization of Frontal Lobe Language Processes and Lateralization of the Posterior Visual Word Processing System
Cerebral Lateralization of Frontal Lobe Language Processes and Lateralization of the Posterior Visual Word Processing System
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DOI：
10.1162/jocn.2008.20043
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发表时间：
2008-04-01
影响因子：
3.2
通讯作者：
Nazir, Tatjana A.
中科院分区：
文献类型：
--
作者：
Cai, Qing;Lavidor, Michal;Nazir, Tatjana A.
参与视觉文字处理的大脑区域迅速偏向左侧大脑半球。人们通常认为这是因为，在绝大多数人中，语言产生的皮质结构偏侧于左半球。然而，另一种假说可能是，视觉文字处理的早期阶段偏侧于左半球，这是因为在处理低水平视觉信息时的内在半球差异，这是区分细粒度视觉形式(如字母)所需的。如果另一种假说是正确的，我们预计，对于参与语言产生的额叶加工的右半球占优势的参与者来说，枕叶后部的加工阶段仍将偏向左半球。通过分析左半球或右半球支配语言产生的母语法语读者的事件相关电位(使用动词生成任务来确定)，我们能够表明，参与视觉文字加工的后枕颞区与语言产生是偏侧的。这一发现可能表明自上而下对后部视觉文字处理区域的发展产生了影响。
The brain areas involved in visual word processing rapidly become lateralized to the left cerebral hemisphere. It is often assumed this is because, in the vast majority of people, cortical structures underlying language production are lateralized to the left hemisphere. An alternative hypothesis, however, might be that the early stages of visual word processing are lateralized to the left hemisphere because of intrinsic hemispheric differences in processing low-level visual information as required for distinguishing fine-grained visual forms such as letters. If the alternative hypothesis was correct, we would expect posterior occipito-temporal processing stages still to be lateralized to the left hemisphere for participants with right hemisphere dominance for the frontal lobe processes involved in language production. By analyzing event-related potentials of native readers of French with either left hemisphere or right hemisphere dominance for language production (determined using a verb generation task), we were able to show that the posterior occipito-temporal areas involved in visual word processing are lateralized to the same hemisphere as language production. This finding could suggest top-down influences in the development of posterior visual word processing areas.