Anodal transcranial direct current stimulation (atDCS) enhances the efficiency of functional brain network communication during auditory attentional control.
Anodal transcranial direct current stimulation (atDCS) enhances the efficiency of functional brain network communication during auditory attentional control.
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DOI：
10.1152/jn.00074.2020
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发表时间：
2020-04
影响因子：
2.5
通讯作者：
Nicolas Zink;Kathleen Kang;Shu-Chen Li;C. Beste
中科院分区：
文献类型：
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作者：
Nicolas Zink;Kathleen Kang;Shu-Chen Li;C. Beste
当我们的大脑面对大量的感官信号时，注意力控制对于选择性地关注相关信息至关重要。图论测度为研究脑网络通信在分离和整合信息方面的效率提供了有力的工具。虽然已经证明atDCS可以在高控制需求的情况下提高听觉注意，但在注意焦点与知觉显著性冲突的情况下，其对功能性脑网络通信的神经生理机制的影响尚不清楚。本研究探讨了不同注意知觉冲突水平下atDCS对网络连通性和θ波振荡功率的影响。我们假设，在需要高度注意控制的条件下，atDCS对网络通信效率的好处将特别明显。30名年轻人参加了一项有强度控制的二分听任务，同时记录了脑电图活动。在交叉设计中，参与者在两个单独的疗程中接受了右额叶atDCS和假刺激。分别使用时频分解和网络效率的图形理论分析（使用“小世界”属性）来量化θ波振荡功率和大脑网络效率。与假刺激相比，在最苛刻的条件下，atDCS对任务效率的影响仅反映在atDCS期间网络效率的增加上。这些发现得到了贝叶斯分析的证实。在高水平的注意-知觉冲突下，atdcs诱导的性能增强伴随着网络效率的提高。图理论测量可以作为一种度量来量化非侵入性脑刺激对大脑信息分离和整合的影响。
Attentional control is crucial for selectively attending to relevant information when our brain is confronted with a multitude of sensory signals. Graph-theoretical measures provide a powerful tool for investigating the efficiency of brain network communication in separating and integrating information. Albeit it has been demonstrated that atDCS can boost auditory attention in situations with high control demands, its effect on neurophysiological mechanisms of functional brain network communication in situations when attentional focus conflicts with perceptual saliency remain unclear. This study investigated the effects of atDCS on network connectivity and theta oscillatory power under different levels of attentional-perceptual conflict. We hypothesized that the benefit of atDCS on network communication efficiency would be particularly apparent in conditions requiring high attentional control. Thirty young adults participated in a dichotic listening task with intensity manipulation while EEG activity was recorded. In a cross-over design, participants underwent right frontal atDCS and sham stimulations in two separate sessions. Time-frequency decomposition and graph-theoretical analyses of network efficiency (using 'small-world' properties) were used, respectively, to quantify theta oscillatory power and brain network efficiency. The atDCS-induced effect on task efficiency in the most demanding condition was mirrored only by an increase in network efficiency during atDCS compared to sham stimulation. These findings are corroborated by Bayesian analyses. AtDCS-induced performance enhancement under high levels of attentional-perceptual conflicts is accompanied by an increase in network efficiency. Graph-theoretical measures can serve as a metric to quantify the effects of non-invasive brain stimulation on the separation and integration of information in the brain.