Black-white differences in stage-specific cancer survival: analysis of seven selected sites.
Black-white differences in stage-specific cancer survival: analysis of seven selected sites.
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特定阶段癌症存活率的黑白差异：对七个选定部位的分析。
DOI：
10.1093/oxfordjournals.aje.a115942
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发表时间：
1991
影响因子：
5
通讯作者：
Merrill,DW
中科院分区：
文献类型：
--
作者：
Ragland,KE;Selvin,S;Merrill,DW
许多研究者注意到，美国黑人的癌症存活率普遍低于白色人群。然而，目前尚不清楚这种差异是否完全由诊断时疾病阶段的差异来解释。本研究使用旧金山-奥克兰（加州）大都会统计区1974-1985年的监测、流行病学和最终结果项目数据，研究黑人和白人之间的生存差异，同时控制诊断时的分期和年龄。检查的癌症部位是那些被认为通过早期发现和治疗可以避免死亡的部位，即结肠、直肠、膀胱、乳腺、子宫颈、子宫体和前列腺。检查每个癌症部位的阶段特异性（局部，区域和远程）生存曲线。结肠癌、男性直肠癌和前列腺癌的部位和分期特异性曲线，辅以比例风险分析，表明无显著的分期特异性种族差异。男性膀胱癌、女性直肠癌和乳腺癌的分期特异性生存差异持续存在。对于女性膀胱癌、宫颈癌和子宫体癌，种族和分期之间的关系更为复杂;对于这些部位，在某些阶段存在种族差异，但不是所有阶段。根据这些研究结果，二级干预计划的后果被认为是七个网站。
A number of reserachers have noted that the black population in the United States generally has less favorable cancer survival than does the white population. It is not clear, however, whether this difference is fully explained by differences in stage of disease at diagnosis. This study uses Surveillance, Epidemiology, and End Results program data from the San Francisco-Oakland (California) Metropolitan Statistical Area for the years 1974–1985 to study survival differences between blacks and whites while controlling for both stage and age at diagnosis. The cancer sites examined are those for which mortality is considered avoidable by early detection and treatment, namely the colon, rectum, bladder, breast, cervix, uterine corpus, and prostate. Stage-specific (local, regional, and remote) survival curves are examined for each cancer site. The site- and stage-specific curves for colon, male rectal, and prostate cancer, supplemented by proportional hazards analyses, indicate no significant stage-specific racial differentials. Stage-specific survival differentials persist for male bladder, female rectal, and breast cancer. The relation between race and stage is more complex for female bladder, cervical, and uterine corpus cancer; for these sites, there is a racial difference at some stages but not all. The consequences for secondary intervention programs are considered for the seven sites in light of these findings.