CARCINOMA OF THE NASOPHARYNX - ANALYSIS OF TREATMENT RESULTS IN 167 CONSECUTIVELY ADMITTED PATIENTS
CARCINOMA OF THE NASOPHARYNX - ANALYSIS OF TREATMENT RESULTS IN 167 CONSECUTIVELY ADMITTED PATIENTS
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DOI：
10.1002/hed.2880140307
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发表时间：
1992-05-01
影响因子：
2.9
通讯作者：
OVERGAARD, J
中科院分区：
文献类型：
--
作者：
JOHANSEN, LV;MESTRE, M;OVERGAARD, J
对连续收治的167例鼻咽癌患者中的159例进行了根治性放疗。根据UICC 1982的分期标准，I期占8%，II期占2%，III期占28%，IV期占61%。颈淋巴结的主要控制率为67%，但与N类无关。20%的患者发生远端失效;这与N分类相关。10年精算校正生存率为37%（I + II期60%，III期49%，IV期27%）。69%的患者出现迟发反应，大多数患者有轻度至中度口干。高血红蛋白的男性比正常范围较低的男性有更好的预后。得出的结论是，T位置和N位置的主要控制是成功最关键的参数。
Radiotherapy with curative intent was administered to 159 of 167 consecutively admitted patients with nasopharyngeal carcinoma. The classification (UICC 1982) gave the staging: stage I 8%, stage II 2%, stage III 28%, and stage IV 61 %.The actuarial local tumor control was 54% and correlated to the T-classification. Primary control of neck nodes was 67% but was not correlated to the N-classes. Distant failure occurred in 20% of the patients; this was correlated to the N-classification. The 10-year actuarially corrected survival rate was 37% (stage I + II 60%, stage III 49%, stage IV 27%). Late reactions were seen in 69%, and most patients had mild to moderate xerostomia. Men with high hemoglobin had a better prognosis than men with values in the lower part of the normal range. It is concluded that primary control in the T- and N-positions is the parameter most crucial to success.