Importance of atopic cough, cough variant asthma and sinobronchial syndrome as causes of chronic cough in the Hokuriku area of Japan
Importance of atopic cough, cough variant asthma and sinobronchial syndrome as causes of chronic cough in the Hokuriku area of Japan
复制标题
DOI：
10.1111/j.1440-1843.2005.00686.x
复制
发表时间：
2005-03-01
期刊：
影响因子：
6.9
通讯作者：
Iwasa, K
中科院分区：
文献类型：
--
作者：
Fujimura, M;Abo, M;Iwasa, K
目的：一项前瞻性的多中心研究进行了阐明慢性咳嗽的原因在Japan.Methodology：所有连续和连续咳嗽患者抱怨咳嗽持续8周或以上，谁访问了我们的诊所从2001年6月1日至12月31日，进行了登记。慢性咳嗽的原因进行诊断的基础上的明确和可能的原因咳嗽的标准，由日本咳嗽研究society.Results建议：在248例患者入组，72例（29.0%）无法进行随访之前，他们的诊断评估已经完成。在176名接受充分评估的患者中，165名患者做出了诊断（93.7%）为单一病因或两种病因之一：特应性咳嗽48例（29.1%）和11例患者咳嗽变异性哮喘46例（27.9%）和9例患者结果：28例（17.7%）患者中，哮喘14例（8.5%），哮喘3例（1.8%），支气管综合征（SBS）14例（8.5%）。结论：特应性咳嗽、喘息性咳嗽（包括咳嗽变异性哮喘和咳嗽为主型哮喘）和SBS是日本慢性咳嗽的主要病因。
Objective: A prospective multicentre study was conducted to elucidate the causes of chronic cough in Japan.Methodology: All consecutive and unselected patients complaining of cough lasting 8 weeks or more, who visited our clinics from 1 June to 31 December 2001, were registered. The causes of chronic cough were diagnosed based on the criteria for definite and probable causes of cough as recommended by the Japanese Cough Research Society.Results: Of the 248 patients enrolled, 72 patients (29.0%) were unavailable for follow up before their diagnostic assessment had been finalized. Among the 176 patients who were adequately assessed, a diagnosis was made in 165 patients (93.7%) either as single cause or as one of two casuses: atopic cough in 48 (29.1%) and 11 patients (6.7%); cough variant asthma in 46 (27.9%) and nine patients (5.5%); cough predominant asthma in 14 (8.5%) and three patients (1.8%); and sinobronchial syndrome (SBS) in 28 (17.7%) and 14 patients (8.5%), respectively. A diagnosis of gastro-oesophageal reflux-associated cough was made in a total of four patients (2.4%).Conclusion: Atopic cough, asthmatic cough consisting of cough variant asthma and cough predominant asthma, and SBS are major causes of chronic cough in Japan.