Informative cluster sizes for subcluster-level covariates and weighted generalized estimating equations.
Informative cluster sizes for subcluster-level covariates and weighted generalized estimating equations.
复制标题
亚集群级协变量和加权广义估计方程的信息群集大小。
DOI:
10.1111/j.1541-0420.2010.01542.x
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发表时间:
2011-09
期刊:
影响因子:
1.9
通讯作者:
Leroux B
中科院分区:
文献类型:
--
作者:
Huang Y;Leroux B
’s cluster-weighted generalized estimating equations (CWGEE) are effective at adjusting for bias due to informative cluster sizes for cluster-level covariates. We show that CWGEE may not perform well, however, for covariates that can take different values within a cluster if the numbers of observations at each covariate level are informative. On the other hand, inverse probability of treatment weighting accounts for informative treatment propensity but not for informative cluster size. Motivated by evaluating the effect of a binary exposure in presence of such types of informativeness, we propose several weighted generalized estimating equation estimators, with weights related to the size of a cluster as well as the distribution of the binary exposure within the cluster. Choice of the weights depends on the population of interest and the nature of the exposure. Through simulation studies, we demonstrate the superior performance of the new estimators compared to existing estimators such as from GEE, CWGEE, and inverse probability of treatment weighted GEE. We demonstrate the use of our method using an example examining covariate effects on the risk of dental caries among small children.
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影响因子:
1.9
作者:
Neuhaus, JM;Kalbfleisch, JD
通讯作者:
Kalbfleisch, JD
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Imbens, GW
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Imbens, GW
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ROSENBAUM, PR
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