The ICRP computational framework for internal dose assessment for reference adults: specific absorbed fractions ICRP PUBLICATION 133
The ICRP computational framework for internal dose assessment for reference adults: specific absorbed fractions ICRP PUBLICATION 133
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DOI：
10.1177/0146645316661077
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发表时间：
2016-11-01
影响因子：
--
通讯作者：
Petoussi-Henss, N.
中科院分区：
文献类型：
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作者：
Bolch, W. E.;Jokisch, D.;Petoussi-Henss, N.
用于评估放射性核素内照射的剂量系数是放射性防护量，给出摄入或吸入后每次摄入放射性核素的器官当量剂量或有效剂量。在国际辐射防护委员会（ICRP）的放射性核素职业摄入量（OIR）出版物系列中，根据建立沉积器官（源区域）内时间积分活动的需要，介绍了人体内内化放射性核素分布的新生物动力学模型。这一系列出版物取代了第30号和第68号出版物（辐射防护委员会，1979年、1980年、1981年、1988年、1994年b）。此外，计算剂量系数所需的其他基本数据是放射性核素衰变数据（发射辐射的能量和产额），这些数据在出版物107（ICRP，2008）中给出，以及比吸收分数（SAF）值-定义为源组织区域中发射的粒子能量沉积在靶组织区域中的分数（单位靶组织质量）。该出版物为与出版物89和110（ICRP，2002年，2009年）中定义的参考成年男性和参考成年女性器官中内化放射性核素活性相关的SAF提供了技术基础。SAF给出了单能光子，电子，α粒子和裂变谱中子在相关能量范围内的均匀分布。电子SAF包括能量沉积的碰撞和辐射分量。SAF数据与OIR出版物系列的生物动力学模型的源和靶器官以及出版物100（ICRP，2006）人类消化道模型和出版物66（ICRP，1994 a）人类呼吸道模型相匹配，后者在出版物130（ICRP，2015）中进行了修订。该出版物进一步概述了计算方法和命名的方式一致的核医学应用程序中使用的内部剂量评估。粒子特定的和能量依赖的SAF的数值数据以电子格式给出，用于OIR出版物系列的呼吸道、消化道和全身生物动力学模型的数值耦合。(C)2016 ICRP。由SAGE发布。
Dose coefficients for assessment of internal exposures to radionuclides are radiological protection quantities giving either the organ equivalent dose or effective dose per intake of radionuclide following ingestion or inhalation. In the International Commission on Radiological Protection's (ICRP) Occupational Intakes of Radionuclides (OIR) publication series, new biokinetic models for distribution of internalised radionuclides in the human body are presented as needed for establishing time-integrated activity within organs of deposition (source regions). This series of publications replaces Publications 30 and 68 (ICRP, 1979, 1980, 1981, 1988, 1994b). In addition, other fundamental data needed for computation of the dose coefficients are radionuclide decay data (energies and yields of emitted radiations), which are given in Publication 107 (ICRP, 2008), and specific absorbed fraction (SAF) values - defined as the fraction of the particle energy emitted in a source tissue region that is deposited in a target tissue region per mass of target tissue. This publication provides the technical basis for SAFs relevant to internalised radionuclide activity in the organs of Reference Adult Male and Reference Adult Female as defined in Publications 89 and 110 (ICRP, 2002, 2009). SAFs are given for uniform distributions of mono-energetic photons, electrons, alpha particles, and fission-spectrum neutrons over a range of relevant energies. Electron SAFs include both collision and radiative components of energy deposition. SAF data are matched to source and target organs of the biokinetic models of the OIR publication series, as well as the Publication 100 (ICRP, 2006) Human Alimentary Tract Model and the Publication 66 (ICRP, 1994a) Human Respiratory Tract Model, the latter as revised within Publication 130 (ICRP, 2015). This publication further outlines the computational methodology and nomenclature for assessment of internal dose in a manner consistent with that used for nuclear medicine applications. Numerical data for particle-specific and energy-dependent SAFs are given in electronic format for numerical coupling to the respiratory tract, alimentary tract, and systemic biokinetic models of the OIR publication series. (C) 2016 ICRP. Published by SAGE.