Conjugated polymer dots for multiphoton fluorescence imaging
Conjugated polymer dots for multiphoton fluorescence imaging
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DOI：
10.1021/ja074590d
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发表时间：
2007-10-31
影响因子：
15
通讯作者：
McNeill, Jason
中科院分区：
文献类型：
--
作者：
Wu, Changfeng;Szymanski, Craig;McNeill, Jason
本文报道了共轭聚合物量子点的双光子激发荧光。作为一类新型双光子荧光探针，CPdot的双光子作用截面高达2.0 x 10（5）GM，据我们所知，这是迄今为止报道的最大的纳米颗粒。截面值比常规荧光染料高3-4个数量级，比无机量子点高一个数量级。使用相对低的激光功率实现单粒子荧光成像。
We report on the two-photon excited fluorescence of conjugated polymer dots (CPdots). As a new class of two-photon fluorescent probes, CPdots exhibit two-photon action cross sections as high as 2.0 x 10(5) GM, to our knowledge, the largest reported thus far for a nanoparticle. The cross section values are 3-4 orders of magnitude higher than those of conventional fluorescent dyes and an order of magnitude higher than those of inorganic quantum dots. Single particle fluorescence imaging was achieved using relatively low laser power.