Corneal biomechanical characteristics measured by the CorVis Scheimpflug technology in eyes with primary open-angle glaucoma and normal eyes
Corneal biomechanical characteristics measured by the CorVis Scheimpflug technology in eyes with primary open-angle glaucoma and normal eyes
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DOI：
10.1111/aos.12672
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发表时间：
2016-08-01
影响因子：
3.4
通讯作者：
Huang, Yifei
中科院分区：
文献类型：
--
作者：
Tian, Lei;Wang, Dajiang;Huang, Yifei
PurposeTo评估角膜可视化Scheimpflug技术（CorVis ST，Oculus）的角膜生物力学性能的眼睛与原发性开角型青光眼（POAG）和正常对照眼。方法一个比较横断面研究，包括42例POAG患者和60名正常对照组匹配的眼内压（IOP）和中央角膜厚度（CCT）。用Goldmann压平眼压计（GAT）测量IOP。分别使用Pentacam（Oculus）和CorVis ST测量角膜断层扫描和生物力学参数。比较各组角膜生物力学特性，并评价角膜生物力学参数与眼部特征之间的相关性。结果POAG眼与正常眼CorVis ST的第一次压平速度（V-in）、第二次压平时间（A-time（2））、峰值距离（PD）和变形幅度（DA）均有显著性差异。在单因素分析中，两组中DA与IOP呈负相关。对于所有生物力学参数，ROC曲线下面积为
PurposeTo evaluate the biomechanical properties of the cornea using Corneal Visualization Scheimpflug Technology (CorVis ST, Oculus) in eyes with primary open-angle glaucoma (POAG) and normal control eyes.MethodsA comparative cross-sectional study that included 42 patients with POAG and 60 normal control subjects matched for intraocular pressure (IOP) and central corneal thickness (CCT). IOP was measured with a Goldmann applanation tonometer (GAT). Corneal tomography and biomechanical parameters were measured with Pentacam (Oculus) and CorVis ST, respectively. Corneal biomechanical properties were compared between groups, and the associations between corneal biomechanical parameters and ocular characteristics were evaluated. Receiver operating characteristic (ROC) curves were used to establish a cut-off value for the biomechanical parameters.ResultsThe following parameters of the CorVis ST showed a significant difference between eyes with POAG and normal eyes: first applanation velocity (V-in), second applanation time (A-time(2)), peak distance (PD) and deformation amplitude (DA). In the univariate analysis, DA was negatively correlated with IOP in both groups. For all biomechanical parameters, the areas under the ROC curve were