MAGNETICALLY INDUCED MUSCLE-CONTRACTION IS CAUSED BY MOTOR-NERVE STIMULATION AND NOT BY DIRECT MUSCLE ACTIVATION
MAGNETICALLY INDUCED MUSCLE-CONTRACTION IS CAUSED BY MOTOR-NERVE STIMULATION AND NOT BY DIRECT MUSCLE ACTIVATION
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DOI：
10.1002/mus.880171007
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发表时间：
1994-10-01
期刊：
影响因子：
3.4
通讯作者：
CONRAD, B
中科院分区：
文献类型：
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作者：
MACHETANZ, J;BISCHOFF, C;CONRAD, B
当磁力刺激周围神经时，会观察到线圈下方肌肉的局部协同收缩。我们评估了这种收缩是否由以下原因引起：（1）运动神经的磁刺激，或（2）肌膜的直接去极化。使用直接放置在肌肉上方的线圈对正常受试者的腕伸肌进行磁刺激。然后使用局部箭毒化技术用阿曲库铵阻断神经肌肉传递。作为参考，对桡神经进行电刺激。每 10 秒交替施加一次磁刺激和电刺激。在约 70 分钟的时间内（包括完全神经肌肉阻滞阶段）等长测量手腕伸展的抽搐力。在整个实验期间，磁刺激和电刺激引起的抽搐幅度是相等的。这些结果表明，磁刺激后的肌肉协同收缩是由末梢运动神经分支的去极化引起的。 (C) 1994 约翰威利父子公司
When magnetically stimulating peripheral nerves, a local cocontraction of muscle under the coil is observed. We assessed whether this contraction results from: (1) magnetic stimulation of motor nerves, or (2) direct depolarization of the muscle membrane. Wrist extensor muscles of normal subjects were magnetically stimulated with the coil placed directly above the muscle. Neuromuscular transmission was then blocked by atracurium using a technique of local curarization. As a reference, the radial nerve was stimulated electrically. Magnetic and electrical stimuli were applied alternatingly every 10 s. Twitch force of wrist extension was measured isometrically over a period of about 70 min including the phase of complete neuromuscular block. Twitch amplitudes elicited by magnetic and electrical stimuli were equivalent during the whole experiment. These results suggest that muscle cocontraction following magnetic stimulation results from depolarization of terminal motor nerve branches. (C) 1994 John Wiley and Sons, Inc.