First human transvenous coronary angiography at the European Synchrotron Radiation Facility
First human transvenous coronary angiography at the European Synchrotron Radiation Facility
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DOI：
10.1088/0031-9155/45/9/102
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发表时间：
2000-09-01
影响因子：
3.5
通讯作者：
Le Bas, JF
中科院分区：
文献类型：
--
作者：
Elleaume, H;Fiedler, S;Le Bas, JF
本文报道了欧洲同步辐射装置(ESRF)医疗光束线的首次运行。该血管造影术项目的目标是开发一种降低风险的成像技术，可用于冠状动脉介入治疗后的患者随访。在静脉注射造影剂(碘)后，产生两个单色光束的图像，将碘K边缘包围起来。这两个测量值的对数相减得到了可以精确量化的碘增强图像。设计了一种研究方案来评估该方法的性能，并与传统技术进行了比较。纳入该方案的患者以前曾接受过血管成形术。如果怀疑ARE狭窄，在接下来的几天内，患者将在ESRF和医院用传统技术进行成像。本文报道了第一批患者的研究结果。到目前为止，已对8名患者进行了成像，并获得了良好的图像质量。
The first operation of the European Synchrotron Radiation Facility (ESRF) medical beamline is reported in this paper. The goal of the angiography project is to develop a reduced risk imaging technique, which can be used to follow up patients after coronary intervention. After the intravenous injection of a contrast agent (iodine) two images are produced with monochromatic beams, bracketing the iodine K-edge. The logarithmic subtraction of the two measurements results in an iodine-enhanced image, which can be precisely quantified. A research protocol has been designed to evaluate the performances of this method in comparison with the conventional technique. Patients included in the protocol have previously undergone angioplasty. If are-stenosis is suspected, the patient is imaged both at the ESRF and at the hospital with the conventional technique, within the next few days. This paper reports the results obtained with the first patients. To date, eight patients have been imaged and excellent image quality was obtained.