Toward single breath-hold whole-heart coverage coronary MRA using highly accelerated parallel imaging with a 32-channel MR system
Toward single breath-hold whole-heart coverage coronary MRA using highly accelerated parallel imaging with a 32-channel MR system
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DOI：
10.1002/mrm.20923
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发表时间：
2006-07-01
影响因子：
3.3
通讯作者：
Sodickson, Daniel K.
中科院分区：
文献类型：
--
作者：
Niendorf, Thoralf;Hardy, Christopher J.;Sodickson, Daniel K.
冠状动脉磁共振血管成像(CMRA)通常局限于获取多个靶层，其覆盖范围受信噪比(SNR)、生理运动和扫描时间等相互竞争的限制。这项工作通过演示使用32通道线圈阵列和接收器系统进行高速容量屏气CMRA的技术可行性来解决这些障碍。在非加速CMRA研究中使用32单元阵列提供了比传统心脏优化相控阵线圈高达40%的基线信噪比，从而显著提高了图像质量并改善了冠状动脉的轮廓。适度的加速被用来将靶向多斜板用于定制冠状动脉覆盖的屏气持续时间缩短到10 S。最后，高净加速与3D稳态自由进动技术的信噪比优势相结合，在单次屏气中实现了以前无法实现的冠状动脉的全面体积覆盖。讨论了这种简化的容积成像方法的优点和局限性，并考虑了它对冠状动脉MRA的意义。
Coronary MR angiography (CMRA) is generally confined to the acquisition of multiple targeted slabs with coverage dictated by the competing constraints of signal-to-noise ratio (SNR), physiological motion, and scan time. This work addresses these obstacles by demonstrating the technical feasibility of using a 32-channel coil array and receiver system for highly accelerated volumetric breath-hold CMRA. The use of the 32-element array in unaccelerated CMRA studies provided a baseline SNR increase of as much as 40% over conventional cardiac-optimized phased array coils, which resulted in substantially enhanced image quality and improved delineation of the coronary arteries. Modest accelerations were used to reduce breath-hold durations for tailored coverage of the coronary arteries using targeted mufti-oblique slabs to as little as 10 s. Finally, high net accelerations were combined with the SNR advantages of a 3D steady-state free precession (SSFP) technique to achieve previously unattainable comprehensive volumetric coverage of the coronary arteries in a single breath-hold. The merits and limitations of this simplified volumetric imaging approach are discussed and its implications for coronary MRA are considered.