The impact of body mass index and physical disability on home-based anal self-sampling.
The impact of body mass index and physical disability on home-based anal self-sampling.
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体重指数和身体残疾对家庭肛门自我采样的影响。
DOI：
10.1007/s10552-023-01775-y
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发表时间：
2024
期刊：
影响因子：
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通讯作者：
Nyitray,AlanG
中科院分区：
文献类型：
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作者：
Nitkowski,Jenna;Fernandez,MariaE;Ridolfi,Tim;Chiao,Elizabeth;Giuliano,AnnaR;Schick,Vanessa;Swartz,MichaelD;Smith,JenniferS;Nyitray,AlanG
自我采样越来越多地被用于筛查项目，但迄今为止还没有研究探讨身体特征对自我采样经验的影响。我们的目的是评估是否身体质量指数（BMI）和身体残疾与肛门自我采样difficulty.MethodsWe招募性少数民族男子（SMM）和跨人在密尔沃基，威斯康星州参加肛门癌筛查研究。在2020年1月至2022年8月期间，240名参与者被随机分配到家庭（n= 120）或诊所（n= 120）筛选组。家庭参与者收到邮寄的家庭肛门自我采样套件，并被要求参加基线诊所访视，收集生物特征测量结果。参与者被要求完成一项关于他们使用该工具包的经验的调查。本研究利用了使用家庭套件并完成基线诊所访视和拭子后调查的参与者的数据（n= 82）。我们评估了BMI和身体残疾的影响报告身体或拭子定位difficuls.ResultsMost参与者报告没有或很少的身体定位（90.3%）或拭子定位（82.9%）的困难。较高的BMI与报告的体位（aOR = 1.10，95% CI 1.003- 1.20，p = 0.04）和拭子定位（aOR = 1.11，95% CI 1.02- 1.20，p = 0.01）困难较大显著相关。虽然不显著，但那些说身体定位困难的参与者有身体残疾的几率高出2.79。标本充足性没有不同的BMI类别（p= 0.76）或身体残疾（p= 0.88）。ConclusionAnal自我采样可能是一个可行的选择，以达到肥胖的人可能更有可能避免筛选，由于体重相关的障碍。
PurposeSelf-sampling is increasingly being used in screening programs, yet no studies to date have examined the impact of bodily characteristics on self-sampling experiences. Our objective was to assess whether body mass index (BMI) and physical disability were associated with anal self-sampling difficulty.MethodsWe recruited sexual minority men (SMM) and trans persons in Milwaukee, Wisconsin to participate in an anal cancer screening study. Between January 2020 and August 2022, 240 participants were randomized to a home (n= 120) or clinic (n= 120) screening arm. Home participants received a mailed at-home anal self-sampling kit and were asked to attend a baseline clinic visit where biometric measurements were collected. Participants were asked to complete a survey about their experience with the kit. This research utilized data from participants who used the at-home kit and completed a baseline clinic visit and post-swab survey (n= 82). We assessed the impact of BMI and physical disability on reported body or swab positioning difficulty.ResultsMost participants reported no or little difficulty with body positioning (90.3%) or swab positioning (82.9%). Higher BMI was significantly associated with greater reported difficulty with body positioning (aOR = 1.10, 95% CI 1.003–1.20,p= 0.04) and swab positioning (aOR = 1.11, 95% CI 1.02–1.20,p= 0.01). Although not significant, participants who said body positioning was difficult had 2.79 higher odds of having a physical disability. Specimen adequacy did not differ by BMI category (p= 0.76) or physical disability (p= 0.88).ConclusionAnal self-sampling may be a viable option to reach obese persons who may be more likely to avoid screening due to weight-related barriers.