Three Different Dimerizations of 2-Bromo-3-methyl-1,4-naphthoquinones
Three Different Dimerizations of 2-Bromo-3-methyl-1,4-naphthoquinones
复制标题
2-溴-3-甲基-1,4-萘醌的三种不同二聚化
DOI：
10.1021/jo300696m
复制
发表时间：
2012
期刊：
影响因子：
--
通讯作者：
K
中科院分区：
文献类型：
--
作者：
Azuma;S.; Nishio;K.; Kubo;K.; Sasamori;T.; Tokitoh;N.; Kuramochi;K.; Tsubaki;K
三种具有不同骨架结构的二聚萘醌可以由2-溴-3-甲基-1,4-萘醌一步制备。 2,2'-二聚萘醌是通过乙烯基锡烷通过一锅Stille型反应制备的。氧杂平是通过 1,4-二羟基萘物质通过意想不到的多米诺骨牌反应形成的。环氧化物是通过 Michael/Darzens 反应通过茶醌甲基化物形成的。
Three types of dimeric naphthoquinones, which possess structurally diverse skeletons, can be prepared in one step from 2-bromo-3-methyl-1,4-naphthoquinones. 2,2′-Dimeric naphthoquinones were prepared by a one-pot Stille-type reaction via vinylstannanes. Oxepines are formed by unexpected domino reactions via 1,4-dihydroxynaphthalene species. Epoxides are formed by a Michael/Darzens reaction via theo-quinone methides.