Synthesis and study of the mutagenic activity of di(indeno[2,1-b]indolyl)- and di(indeno[2,1-b]pyrrolyl)methanes and -dimethylsilanes

Synthesis and study of the mutagenic activity of di(indeno[2,1-b]indolyl)- and di(indeno[2,1-b]pyrrolyl)methanes and -dimethylsilanes
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DOI:
10.1023/a:1012745325790
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发表时间:
2001-08-01
影响因子:
1.7
通讯作者:
Lyubimova, IK
Lyubimova, IK
中科院分区:
化学4区
文献类型:
--
作者:
Nifant'ev, IE;Kashulin, IA;Lyubimova, IK

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合成了含有吲哚并[2,1-b]吲哚和吲哚并[2,1-b]吡咯基片段的二烷基二甲基硅烷和二烷基甲烷。用鼠伤寒沙门氏菌标准菌株TA 1537、TA 98、TA 100按Ames标准检测其致突变活性。
Dihetaryldimethylsilanes and dihetarylmethanes containing indeno[2,1-b]indolyl and indeno[2, 1-b]pyrrolyl fragments were synthesized. Their mutagenic activity was tested according to Ames with standard test strains Salmonella typhimurium TA 1537, TA 98, and TA 100.