Delayed time to defibrillation after in-hospital cardiac arrest
Delayed time to defibrillation after in-hospital cardiac arrest
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DOI：
10.1056/nejmoa0706467
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发表时间：
2008-01-03
影响因子：
158.5
通讯作者：
Nallamothu, Brahmajee K.
中科院分区：
文献类型：
--
作者：
Chan, Paul S.;Krumholz, Harlan M.;Nallamothu, Brahmajee K.
背景：专家指南提倡在由室性心律失常引起的院内心脏骤停后2分钟内除颤。然而，关于美国延迟除颤的患病率及其对生存的影响的经验数据有限。方法：我们在参与全国心肺复苏登记的369家医院中确定了6789例因心室颤动或无脉性室性心动过速而发生心脏骤停的患者。使用多变量逻辑回归，我们确定了与延迟除颤相关的特征。然后，在调整了患者和医院特征的差异后，我们检查了延迟除颤（超过2分钟）与存活至出院之间的关系。结果：除颤总中位时间为1分钟(四分位数范围，
Background: Expert guidelines advocate defibrillation within 2 minutes after an in-hospital cardiac arrest caused by ventricular arrhythmia. However, empirical data on the prevalence of delayed defibrillation in the United States and its effect on survival are limited.Methods: We identified 6789 patients who had cardiac arrest due to ventricular fibrillation or pulseless ventricular tachycardia at 369 hospitals participating in the National Registry of Cardiopulmonary Resuscitation. Using multivariable logistic regression, we identified characteristics associated with delayed defibrillation. We then examined the association between delayed defibrillation (more than 2 minutes) and survival to discharge after adjusting for differences in patient and hospital characteristics.Results: The overall median time to defibrillation was 1 minute (interquartile range,