A patient with diffuse cutaneous systemic sclerosis complicated by antineutrophil-cytoplasmic antibody-associated vasculitis exhibiting honeycomb lung without volume loss.
A patient with diffuse cutaneous systemic sclerosis complicated by antineutrophil-cytoplasmic antibody-associated vasculitis exhibiting honeycomb lung without volume loss.
复制标题
一名患有弥漫性皮肤系统性硬化症并发抗中性粒细胞胞浆抗体相关性血管炎的患者，表现出蜂窝状肺，无容量损失。
DOI：
10.2169/internalmedicine.53.1599
复制
发表时间：
2014
影响因子：
1.2
通讯作者：
A. Mimori
中科院分区：
文献类型：
--
作者：
H. Yamashita;Y. Takahashi;H. Kaneko;T. Kano;A. Mimori
我们在此报告了一名72岁女性弥漫性皮肤系统性硬化症（SSc）并发抗中性粒细胞胞浆抗体（ANCA）相关血管炎的病例，她表现出蜂窝状肺，但没有体积损失。入院时，胸部计算机断层扫描（CT）显示蜂窝肺，除间隔壁密度增加外，无容量损失。肾活检显示全球硬化和细胞新月体形成。随后发生多发性单神经炎，并给予环磷酰胺类固醇脉冲治疗。重复胸部CT显示蜂窝肺无变化;但是，观察到间隔壁的整体密度降低。有必要认识到，血管炎可能发生在SSc患者中，这些患者表现出蜂窝肺而没有容量损失。
We herein report the case of a 72-year-old woman with diffuse cutaneous systemic sclerosis (SSc) complicated by antineutrophil cytoplasmic antibody (ANCA)-associated vasculitis who exhibited honeycomb lung without volume loss. On admission, chest computed tomography (CT) revealed honeycomb lung without volume loss in addition to increased density of the partition walls. A renal biopsy revealed global sclerosis and cellular crescent formation. Mononeuritis multiple subsequently occurred, and steroid pulse therapy with cyclophosphamide was administered. Repeat chest CT showed that the honeycomb lung was unchanged; however, overall reduced density of the partition walls was observed. It is necessary to recognise that vasculitis may develop in SSc patients who exhibit honeycomb lung without volume loss.