Synthesis of cyclic dienamide using ruthenium-catalyzed ring-closing metathesis of ene-ynamide.
Synthesis of cyclic dienamide using ruthenium-catalyzed ring-closing metathesis of ene-ynamide.
复制标题
DOI：
10.1021/ol017298y
复制
发表时间：
2002-02
期刊：
影响因子：
5.2
通讯作者：
Nozomi Saito;Yuka Sato;M. Mori*
中科院分区：
文献类型：
--
作者：
Nozomi Saito;Yuka Sato;M. Mori*
[反应：使用第二代Grubbs催化剂进行的烯酰胺的闭环复分解反应以高产率产生了具有二烯酰胺部分的含氮杂环。环化产物与亲双烯体的Diels-Alder反应顺利进行，得到双环或三环化合物。
[reaction: see text] Ring-closing metathesis of ene-ynamide using the second-generation Grubbs' catalyst produced nitrogen-containing heterocycles, which have dienamide moieties, in high yields. Diels-Alder reaction of the cyclized product and dienophile proceeded smoothly to afford a bi- or tricyclic compound.