Asthma and Chronic Obstructive Pulmonary Disease (COPD) - Differences and Similarities.
Asthma and Chronic Obstructive Pulmonary Disease (COPD) - Differences and Similarities.
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DOI：
10.5455/msm.2012.24.100-105
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发表时间：
2012
期刊：
影响因子：
--
通讯作者：
Ustamujic A
中科院分区：
文献类型：
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作者：
Cukic V;Lovre V;Dragisic D;Ustamujic A
支气管哮喘和COPD（慢性阻塞性肺病）是影响全世界数百万人的阻塞性肺病。哮喘是一个严重的全球性健康问题，估计有3亿人受到影响。COPD是慢性病发病率和死亡率的主要原因之一，也是世界范围内的主要公共卫生问题之一。COPD是世界上第四大死亡原因，并且可以预测其患病率和死亡率的进一步增加。虽然哮喘和COPD有许多相似之处，但它们也有许多不同之处。它们是两种不同的疾病，在病因、症状、气道炎症类型、炎性细胞、介质、炎症后果、对治疗的反应、病程方面存在差异。严重哮喘和COPD的气道炎症有一些相似之处，并且对这两种疾病的联合治疗有良好的反应，这表明它们具有一些相似的病理生理特征。本文的目的是显示这两种疾病之间的相似性和差异。今天，哮喘和COPD还不能完全治愈，没有得到足够的识别和治疗，治疗仍在发展中。但在未来更好地了解病理，充分识别和治疗，可能是新的药物，将提供更好的生活质量，降低发病率和死亡率的这些患者。
Bronchial asthma and COPD (chronic obstructive pulmonary disease) are obstructive pulmonary diseases that affected millions of people all over the world. Asthma is a serious global health problem with an estimated 300 million affected individuals. COPD is one of the major causes of chronic morbidity and mortality and one of the major public health problems worldwide. COPD is the fourth leading cause of death in the world and further increases in its prevalence and mortality can be predicted. Although asthma and COPD have many similarities, they also have many differences. They are two different diseases with differences in etiology, symptoms, type of airway inflammation, inflammatory cells, mediators, consequences of inflammation, response to therapy, course. Some similarities in airway inflammation in severe asthma and COPD and good response to combined therapy in both of these diseases suggest that they have some similar patophysiologic characteristics. The aim of this article is to show similarities and differences between these two diseases. Today asthma and COPD are not fully curable, not identified enough and not treated enough and the therapy is still developing. But in future better understanding of pathology, adequate identifying and treatment, may be and new drugs, will provide a much better quality of life, reduced morbidity and mortality of these patients.