Assessing the magnetic resonance imaging in determining the depth of invasion of tongue cancer
Assessing the magnetic resonance imaging in determining the depth of invasion of tongue cancer
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DOI：
10.1111/odi.13579
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发表时间：
2020-08-16
期刊：
影响因子：
3.8
通讯作者：
Zhang, Zhi-Yuan
中科院分区：
文献类型：
--
作者：
Fu, Jin-Ye;Zhu, Ling;Zhang, Zhi-Yuan
目的通过与病理对照，评价磁共振成像(MRI)对舌癌肿瘤侵袭深度(DOI)的预测价值，并探讨其作为判断舌癌淋巴结转移的临界值。对象与方法对156例新诊断的舌癌患者进行回顾性分析。通过皮尔逊相关系数和配对t检验，将MRI测量的肿瘤DOI与病理结果进行比较。将MRI获得的DOI与病理DOI的准确性进行比较。通过受试者工作特征曲线计算MRI获得的DOI与颈淋巴结转移的关系。结果MRI测量的肿瘤DOI与病理结果有很好的相关性，相关系数为0.77。MRI获得的DOI比病理大3.4 mm(28%)。MRI判断病理性DOI的准确率为67.9%。MRI获得的DOI判断舌癌淋巴结转移的临界值为10.5 mm。结论磁共振成像可作为确定舌癌肿瘤DOI的参考指标。MRI获得的DOI大于10.5 mm的肿瘤在初次手术时应同时行颈淋巴清扫术。
Objectives To assess the magnetic resonance imaging (MRI) in predicting tumour's depth of invasion (DOI) of tongue cancer by comparing to pathology and to determine the cut-off value of MRI-derived DOI for lymph node metastasis. Patients and methods In a retrospective analysis, 156 patients with newly diagnosed tongue cancer were included. Tumour's DOI was compared between MRI measurement and pathology by Pearson correlation coefficient and pairedttest. The accuracy of MRI-derived DOI was compared to the pathological DOI. The relationship between MRI-derived DOI and cervical lymph node metastasis was calculated by receiver operating characteristic curve. Results Tumour's DOI was well correlated between MRI measurement and pathology with correlation coefficients of 0.77. MRI-derived DOI was 3.4 mm (28%) larger than pathology. The accuracy of MRI in deciding pathological DOI was 67.9%. The cut-off value of MRI-derived DOI was 10.5 mm for lymph node metastasis of tongue cancer. Conclusion Magnetic resonance imaging can be used as a reference to determine tumour's DOI of tongue cancer. Tumour with MRI-derived DOI larger than 10.5 mm deserves simultaneous neck dissection at initial surgery.