What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study.
What Is the Impact of COVID-19 Pandemic on Patients with Pre-Existing Mood or Anxiety Disorder? An Observational Prospective Study.
复制标题
DOI：
10.3390/medicina57040304
复制
发表时间：
2021-03-24
期刊：
影响因子：
--
通讯作者：
Necci R
中科院分区：
文献类型：
--
作者：
Tundo A;Betro' S;Necci R
背景与目的：本观察性前瞻性研究旨在探讨大流行应激对已有情绪、焦虑和强迫症患者的心理和精神病理影响。材料和方法：该研究包括386名连续患者，招募时间为2020年3月10日至6月30日，在意大利罗马精神病理学研究所接受治疗，年龄≥18岁，符合DSM-5重度抑郁症（MDD）（35.2%）、双相I型（BD-I）（21.5%）或II型（BD-II）（28.8%）障碍、强迫症（OCD）（7.5%）、恐慌症（PD）（7.0%）或社交焦虑（SA）标准。共有34.2%的患者终生共病I轴障碍，15.3%的患者有酒精/药物滥用障碍。通过半结构化访谈，我们调查了COVID-19压力对患者的影响是否与其家人和朋友相似、更高或更低，以及对于复发/症状恶化的患者，临床状况恶化与大流行压力之间是否存在关系。结果：与家人和朋友的心理影响相比，52.1%的样本与家人和朋友的心理影响相似，37.1%的样本较好，10.8%的样本较差。在21例（5.4%）患者中，压力引发复发或加重症状。与MDD患者相比，强迫症患者因大流行应激而加重的比率更高（p = 0.033），尽管总体而言，在初次诊断中，χ2检验无显著性差异（χ2 = 8.368; p = 0.057）。结论：我们门诊患者COVID-19应激的心理和精神病理后果非常温和。封锁期间提供的持续护理可以解释这些结果。
Background and Objectives: This observational prospective study aims to examine the psychological and psychopathological impact of the pandemic stress on patients with pre-existing mood, anxiety and obsessive–compulsive disorders. Materials and Methods: The study includes 386 consecutive patients recruited from 10 March to 30 June 2020 among those being treated at the Institute of Psychopathology in Rome (Italy) with an age ≥18 years and meeting DSM-5 criteria for major depressive disorder (MDD) (35.2%), bipolar I (BD-I) (21.5%) or II (BD-II) (28.8%) disorder, obsessive–compulsive disorder (OCD) (7.5%), panic disorder (PD) (7.0%) or social anxiety (SA). A total of 34.2% had lifetime comorbid Axis I disorders and 15.3% had alcohol/drug abuse disorders. Using a semi-structured interview, we investigated if the impact of COVID-19 stress for patients has been similar, higher or lower than that of their family and friends and, for patients with relapse/symptoms worsening, if there was a relationship between the clinical condition worsening and the pandemic stress. Results: Compared with that experienced by their family members and friends, the psychological impact of pandemic stress was similar in 52.1% of the sample, better in 37.1% and worse in 10.8%. In 21 patients (5.4%), the stress triggered a recurrence or worsened the symptoms. Patients with OCD had a higher rate of worsening due to pandemic stress compared to patients with MDD (p = 0.033), although, overall, the χ2 test was not significant among primary diagnoses (χ2 = 8.368; p = 0.057). Conclusions: The psychological and psychopathological consequences of COVID-19 stress in our outpatients were very modest. The continuity of care offered during the lockdown could explain the results.
登录
查看更多内容
影响因子：
4.7
作者：
Benatti, Beatrice;Albert, Umberto;Dell'Osso, Bernardo
通讯作者：
Dell'Osso, Bernardo
影响因子：
6.9
作者：
Davidson, JRT;Miner, CM;Potts, NLS
通讯作者：
Potts, NLS
影响因子：
5.1
作者：
Plunkett, R.;Costello, S.;Hallahan, B.
通讯作者：
Hallahan, B.
影响因子：
15.1
作者：
Hao, Fengyi;Tan, Wanqiu;Tam, Wilson
通讯作者：
Tam, Wilson
影响因子：
3.7
作者：
Sun, Yan;Li, Yangyang;Shi, Jie
通讯作者：
Shi, Jie