The Emerging Spectrum of Somatic Mutation in Rheumatic Disease: Clonal Hematopoiesis Connects Aging With Giant Cell Arteritis.
The Emerging Spectrum of Somatic Mutation in Rheumatic Disease: Clonal Hematopoiesis Connects Aging With Giant Cell Arteritis.
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风湿病中体细胞突变的新谱：克隆造血将衰老与巨细胞动脉炎联系起来。
DOI：
10.1002/art.42745
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发表时间：
2023
期刊：
影响因子：
--
通讯作者：
Tsao,BettyP
中科院分区：
文献类型：
--
作者：
Bucala,Richard;Tsao,BettyP
就风湿病中出现的体细胞突变谱，特别是克隆性造血与巨细胞性动脉炎(GCA)之间的联系，发表了一篇社论。它强调了与年龄相关的克隆性造血的发生率，它与各种慢性疾病的炎症病理的关系，以及Robinette等人对克隆性造血在GCA发病机制中的作用的研究。
An editorial is presented expressing views on the emerging spectrum of somatic mutations in rheumatic disease, particularly the connection between clonal hematopoiesis and giant cell arteritis (GCA). It highlights the age-related incidence of clonal hematopoiesis, its association with inflammatory pathologies in various chronic diseases, and the study by Robinette et al investigating the role of clonal hematopoiesis in GCA pathogenesis.