Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study
Epidemiological features of rosacea in Changsha, China: A population-based, cross-sectional study
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中国长沙市红斑痤疮流行病学特征：基于人群的横断面研究
DOI：
10.1111/1346-8138.15301
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发表时间：
2020-05-01
影响因子：
3.1
通讯作者：
Xie Hongfu
中科院分区：
文献类型：
--
作者：
Li Jinglin;Wang Ben;Xie Hongfu
酒渣鼻是一种常见的慢性皮肤病，病因不明。虽然欧洲和北美的人口患病率在0.2-22%之间，但中国的患病率目前尚不确定。为了解中国地区酒渣鼻的流行现状，我们进行了一项以人群为基础的大型病例对照研究，研究对象为10095人，年龄0~100岁(平均年龄35.5±19.1岁，女性占50.5%)。对中国所在的长沙市中南部15个社区进行了酒渣鼻普查，并由注册皮肤科医生进行皮肤检查。酒渣鼻的发生率为3.48%(95%可信区间，3.13-3.85%)。红斑型分布为血管扩张型占47.6%，丘丘型占35.0%，植块型占17.4%。有家族史者占37.8%，有眼部症状者占31.3%。在女性中，酒渣鼻与黄褐斑、高血压、甲亢和乳腺癌有关联(P<；0.05)，在男性中与甲亢和消化性溃疡也有关联(P<；0.05)。我们的结果提供了中国酒渣鼻流行病学方面的基线信息。
Rosacea is a common chronic skin disorder of unknown etiology. While population prevalence rates range 0.2-22% in Europe and North America, prevalence in China is currently undetermined. We conducted a large population-based case-control study to determine the present epidemiological status of rosacea in China, involving 10 095 participants aged 0-100 years (mean age, 35.5 +/- 19.1; 50.5% female). A census of rosacea among 15 communities in Changsha in south central China was conducted with skin examination by board-certified dermatologists. Rosacea was observed in 3.48% (95% confidence interval, 3.13-3.85%) of the study population. Subtype distribution was erythematotelangiectatic in 47.6%, papulopustular in 35.0% and phymatous in 17.4%. Family history was noted in 37.8% and ocular symptoms in 31.3%. Associations with rosacea were observed for melasma, hypertension, hyperthyroidism and breast cancer in females (P < 0.05), and also for hyperthyroidism and peptic ulcers in males (P < 0.05). Our results provide baseline information about epidemiological aspects of rosacea in China.