RENAL OXYGEN TENSION
RENAL OXYGEN TENSION
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DOI：
10.1038/188671a0
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发表时间：
1960-01-01
期刊：
影响因子：
64.8
通讯作者：
KROG, J
中科院分区：
文献类型：
--
作者：
AUKLAND, K;KROG, J
尿氧分压通常低于肾静脉血的氧分压。当尿液中不含大量还原性物质（如抗坏血酸）时，尿耗氧量非常低，不能解释新鲜骨盆尿液的低氧张力1。据计算，只有微不足道的氧张力梯度可能存在整个小管壁2。因此，低的尿氧分压表明小管系统的某些部分具有比肾静脉血更低的氧分压。参考文献2表明，由于“血浆撇除”3，肾小管周围毛细血管中的氧张力较低，并且在曲小管中确定尿氧张力。然而，由于集合管对水和尿素具有自由渗透性，因此尿液氧张力与髓质氧张力的平衡似乎也是非常可能的。因此，对引入犬肾脏不同区域的铂电极的氧可用性进行了测定。
URINE oxygen tension is regularly lower than the oxygen tension of renal venous blood. When urine does not contain large amounts of reducing substances, for example, ascorbic acid, the urinary oxygen consumption is very low and cannot account for the low oxygen tension of fresh pelvic urine1. It has been calculated that only insignificant oxygen tension gradient may exist across the tubule wall2. The low urine oxygen tension therefore indicates that some segment of the tubule system has a lower oxygen tension then renal venous blood. Reeveset al.2have suggested a low oxygen tension in the peritubular capillaries due to ‘plasma skimming’3, and that urine oxygen tension is determined in the convoluted tubules. As the collecting ducts have been shown to be freely permeable to water and urea, howrever, an equilibration of the urine oxygen tension with medullary oxygen tension as well seems highly probable. Determination of the availability of oxygen to a platinum electrode introduced into the various zones of the dog kidney was therefore undertaken.