The 12-lead electrocardiogram of "healthy" ambulatory subjects with positive Lyme immunoserology.
The 12-lead electrocardiogram of "healthy" ambulatory subjects with positive Lyme immunoserology.
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莱姆病免疫血清学呈阳性的“健康”动态受试者的 12 导联心电图。
DOI：
10.1016/0002-9149(93)90663-w
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发表时间：
1993
期刊：
影响因子：
--
通讯作者：
A. Dlesk
中科院分区：
文献类型：
--
作者：
H. Vidaillet;S. Broste;J. Marx;P. Mccarty;P. Layde;P. Mitchell;A. Dlesk
1977年，Steere等人首次将莱姆病描述为一种独特的临床实体，现在已知莱姆病是由人类感染伯氏疏螺旋体引起的，这种生物主要由硬皮癣传播。2对Tob抗体的血清学检测。Burgdorferi虽然不完美，但仍然是唯一最好的、广泛可用的实验室方法，可以证明接触到有害生物。3早期(II期)莱姆病最常见的心脏表现包括不同程度的房室传导阻滞，包括完全性心脏传导阻滞。这些传导异常已经被12导联心电图和侵入性电生理测试记录下来。4，5尽管在确定疾病患者中这种螺旋体感染的急性表现方面取得了进展，但关于以前的亚临床感染的意义，特别是流行地区未经治疗的无症状的人的莱姆试验“阳性”，没有临床明显的莱姆病病史，知之甚少。这项研究的目的是在莱姆病流行地区的“健康”血清阳性受试者中确定任何可能与接触莱姆螺旋体有关的心电图异常。
First described as a distinct clinical entity by Steere et al1in 1977, Lyme disease is now known to result from human infection with the spirocheteBorrelia burgdorferi, an organism predominantly transmitted byIxodesticks.2Serologic testing for the presence of antibodies toB. burgdorferi, although imperfect, remains the single best, widely available, laboratory method to demonstrate exposure to the offending organism.3The most frequently reported cardiac manifestation of early (stage II) Lyme disease consists of variable degrees of atrioventricular block, including complete heart block. These conduction abnormalities have been documented by 12-lead electrocardiography and invasive electrophysiologic testing.4,5Despite advances in characterizing the acute expressions of this spirochetal infection in patients with definite disease, little has been learned regarding the significance of previous subclinical infection, specifically a “positive” Lyme test in an untreated asymptomatic person in an endemic area, with no history of clinically apparent Lyme disease. The aim of this study was to identify any electrocardiographic abnormalities that may be attributable to exposure to the Lyme spirochete in “healthy” seropositive subjects in a Lyme disease endemic area.