Exercise Causing Thrombosis
Exercise Causing Thrombosis
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DOI：
10.3810/psm.2009.12.1750
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发表时间：
2009-12-01
影响因子：
2.3
通讯作者：
Williams, Andrew
中科院分区：
文献类型：
--
作者：
Adams, Murray;Fell, James;Williams, Andrew
血栓形成倾向是指形成血栓（血栓形成）的倾向增加，这是发病和死亡的主要原因。血栓形成与多种慢性病有关，例如癌症、糖尿病、肾脏疾病和心血管疾病。由于人口老龄化，未来几十年血栓形成的发病率和相关并发症可能会显着增加。人们建议定期锻炼可以降低血栓形成的风险，尽管调查其影响的研究数据不一致，有报告称不同受试者群体的血栓风险增加和降低。年龄、性别、荷尔蒙变化、身体活动、基础疾病和治疗以及身体成分等混杂因素也导致难以评估和确定运动在预防血栓事件方面的精确效果。然而，有证据表明，体力活动有利于降低年轻人和慢性病患者的血栓形成风险。本文旨在总结已知的血栓形成危险因素，并简要回顾运动对普通人群的益处。此外，本文还强调了一组个体中的其他因素（起初）似乎不太可能有血栓形成精英运动员的风险。
Thrombophilia refers to the increased tendency to form blood clots (thrombosis), which is a major cause of morbidity and mortality. Thrombosis is associated with various chronic conditions such as cancer, diabetes, renal disorders, and cardiovascular disease. The incidence and associated complications of thrombosis are likely to increase significantly in the next few decades because of aging populations. Regular exercise has been proposed to decrease the risk of developing thrombosis, although there are inconsistent data from studies investigating its effects, with reports of both increased and decreased thrombotic risk across a variety of subject cohorts. Confounders such as age, gender, hormonal variations, physical activity, underlying disease and treatment, and body composition also contribute to the difficulty in assessing and defining the precise effects of exercise in preventing thrombotic events. However, there is evidence suggesting that physical activity is beneficial for reducing thrombotic risk in younger individuals and those with chronic conditions. This article aims to summarize the known risk factors for thrombosis and briefly review the benefits of exercise in the general population. Furthermore, this article highlights the additional factors in a cohort of individuals that would (at first) appear unlikely to be at risk of thrombosis-elite athletes.