Ewing's sarcoma of the bone: ESMO Clinical Recommendations for diagnosis, treatment and follow-up

Ewing's sarcoma of the bone: ESMO Clinical Recommendations for diagnosis, treatment and follow-up
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DOI:
10.1093/annonc/mdp155
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发表时间:
2009-05-01
期刊:
影响因子:
50.5
通讯作者:
Casali, P. G.
Casali, P. G.
中科院分区:
医学1区
文献类型:
--
作者:
Paulussen, M.;Bielack, S.;Casali, P. G.

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骨尤文肉瘤(ES)/原始神经外胚层肿瘤(PNET)是儿童和青少年中第二常见的原发性恶性骨癌,但也见于成人,特别是皮肤外类型。诊断时的中位年龄为15岁,男性为1.5/1。在白色高加索人中诊断出ES的发病率为每年0.3/100 000,但在非洲和亚洲人群中非常罕见。
Ewing sarcoma (ES)/primitive neuroectodermal tumor (PNET) of bone is the second most common primary malignant bone cancer in children and adolescents, but is also seen in adults, particularly the extraskeletal variety. The median age at diagnosis is 15 years and there is a male predilection of 1.5/1. ES is diagnosed in white Caucasians at an incidence of 0.3/100 000 per year, but is very uncommon in the African and Asian population.