Solvent free amination reactions of aryl bromides at room temperature catalyzed by a (π-allyl)palladium complex bearing a diphosphinidenecyclobutene ligand
Solvent free amination reactions of aryl bromides at room temperature catalyzed by a (π-allyl)palladium complex bearing a diphosphinidenecyclobutene ligand
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DOI：
10.1021/jo049087n
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发表时间：
2004-09-17
影响因子：
3.6
通讯作者：
Ozawa, F
中科院分区：
文献类型：
--
作者：
Gajare, AS;Toyota, K;Ozawa, F
一种空气和湿气稳定的（T-烯丙基）钯配合物，其带有独特的二膦基环丁烯配体，有效地催化芳基溴与胺的胺化反应，其中反应在温和的条件下在室温下用2mol%的催化剂和1当量的t-BuOK在没有溶剂的情况下进行。在这些条件下，胺化。以良好至优异的分离产率获得产物。
An air- and moisture-stable ( T-allyl)palladium complex bearing a unique diphosphinidenecyclobutene ligand effectively catalyzes amination reactions of aryl bromides with amines, where the reactions proceed under mild conditions without solvent, with 2 mol % of catalyst and I equiv of t-BuOK at room temperature. Under these conditions the amination. products were obtained in good to excellent isolated yields.