Cardiovascular Risk Reduction in High-Risk Pediatric Patients A Scientific Statement From the American Heart Association
Cardiovascular Risk Reduction in High-Risk Pediatric Patients A Scientific Statement From the American Heart Association
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DOI：
10.1161/cir.0000000000000618
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发表时间：
2019-03-26
期刊：
影响因子：
37.8
通讯作者：
Zaidi, Ali N.
中科院分区：
文献类型：
--
作者：
de Ferranti, Sarah D.;Steinberger, Julia;Zaidi, Ali N.
这一科学声明提出了临床管理方面的考虑因素，涉及评估和降低选定的早产儿心血管疾病高危人群，包括获得性动脉硬化或动脉粥样硬化。对于每个主题，将回顾儿童和青春期加速获得性冠状动脉疾病和中风的证据，以及青年干预有益的证据。儿童和青少年患心血管疾病的风险可能更高，原因是显著的动脉粥样硬化或动脉硬化危险因素、促进动脉硬化的高危条件、或使个人更容易受到传统心血管危险因素不利影响的冠状动脉或其他心脏或血管异常。在适用的情况下，将参考现有的科学声明和指南，并将描述针对每个环境的风险识别和减少建议。本声明面向为这些年轻患者提供临床护理的儿科心脏病专家、初级保健提供者和专科专家。重点将放在管理和管理的理由上，最大限度地减少关于病理生理学和流行病学的信息。
This scientific statement presents considerations for clinical management regarding the assessment and risk reduction of select pediatric populations at high risk for premature cardiovascular disease, including acquired arteriosclerosis or atherosclerosis. For each topic, the evidence for accelerated acquired coronary artery disease and stroke in childhood and adolescence and the evidence for benefit of interventions in youth will be reviewed. Children and adolescents may be at higher risk for cardiovascular disease because of significant atherosclerotic or arteriosclerotic risk factors, high-risk conditions that promote atherosclerosis, or coronary artery or other cardiac or vascular abnormalities that make the individual more vulnerable to the adverse effects of traditional cardiovascular risk factors. Existing scientific statements and guidelines will be referenced when applicable, and suggestions for risk identification and reduction specific to each setting will be described. This statement is directed toward pediatric cardiologists, primary care providers, and subspecialists who provide clinical care for these young patients. The focus will be on management and justification for management, minimizing information on pathophysiology and epidemiology.