Functional brain imaging: dipole localization and Laplacian methods.
Functional brain imaging: dipole localization and Laplacian methods.
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功能性脑成像：偶极子定位和拉普拉斯方法。
DOI：
10.1016/0042-6989(93)90119-h
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发表时间：
1993
期刊：
影响因子：
1.8
通讯作者：
Purdy,PD
中科院分区：
文献类型：
--
作者：
Srebro,R;Oguz,RM;Hughlett,K;Purdy,PD
两种方法的性能，用于本地化从头皮上测量的诱发电位场的大脑活动，进行了评估，在坦克模型的人的头部。这个物理模型包含一个包裹在聚合物中的人类头骨，模拟大脑和头皮的电阻率和几何形状。偶极定位法将已知偶极源的位置错误定位了几厘米。定位错误是系统性的。偶极子在头部的位置太深。如果头皮场的等电位轮廓在测量范围内闭合，则拉普拉斯方法产生类似于脑表面场（皮层电位场）的场。剪切导致了严重的错误定位的位置的峰值的上皮层电位场。
The performance of two methods, used to localize brain activity from evoked potential fields measured on the scalp, was assessed in a tank model of the human head. This physical model contained a human skull encased in a polymer simulating the resistivity and geometry of brain and scalp. The dipole localization method mislocalized the positions of known dipole sources by several centimeters. The mislocalization was systematic. The dipoles were localized too deeply in the head. The Laplacian method yielded a field resembling die brain surface field (epicortical potential field) provided that the iso-potential contours of the scalp field closed within the measurement range. Clipping resulted in a serious mislocalization of the position of the peak of the epicortical potential field.