Pituitary secretion of growth hormone in response to opioid peptides and opiates is mediated through growth hormone-releasing factor.
Pituitary secretion of growth hormone in response to opioid peptides and opiates is mediated through growth hormone-releasing factor.
复制标题
垂体响应阿片肽和阿片制剂分泌生长激素是通过生长激素释放因子介导的。
DOI：
10.1159/000124147
复制
发表时间：
1985
影响因子：
4.1
通讯作者：
Ling,N
中科院分区：
文献类型：
--
作者：
Wehrenberg,WB;Bloch,B;Ling,N
Passive immunization of rats with an antiserum raised against rat growth hormone-releasing factor (GRF) completely inhibited the growth hormone (GH) response to morphine and β-endorphin but did not alter the prolactin (PRL) response to those two stimuli. These results demonstrate that opiate and opioid peptide stimulation of pituitary GH secretion is mediated through hypothalamic GRF and presents an animal model in which the stimulated secretion of GH and PRL can be specifically dissociated.
