A study on the input‐output function of a nonlinear cochlear transmission‐line model with the function of an outer hair cell model

A study on the input‐output function of a nonlinear cochlear transmission‐line model with the function of an outer hair cell model
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具有外毛细胞模型功能的非线性耳蜗传输线模型的输入输出函数研究

DOI:
10.1121/1.2942920
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发表时间:
2007
影响因子:
2.4
通讯作者:
M. Unoki
M. Unoki
中科院分区:
物理与天体物理3区
文献类型:
--
作者:
Y. Murakami;M. Unoki

文献摘要

被引文献

相似文献

提出了一种具有外毛细胞(OHC)生理功能的非线性耳蜗传输线模型,以研究OHC如何在耳蜗滤波的输入输出(IO)函数中产生非线性。作为OHC模型的生理功能,研究了OHC体细胞运动产生的压力。躯体运动是由随发束位移而变化的换能器电流引起的。由OHC模型产生的压力可以通过电流量线性近似。所提出的模型由中耳模型和耳蜗传输线模型组成,耳蜗传输线模型包括基底膜和淋巴液模型、覆膜模型、毛束模型和OHC模型。该模型的参数设定为从动物数据获得的人类估计值。在仿真结果中,该模型可以解释从生理和心理实验中获得的耳蜗滤波的IO功能。这些...
A nonlinear cochlear transmission‐line model with the physiological function of an outer hair cell (OHC) model is presented to investigate how OHCs produce the nonlinearity in the input‐output (IO) functions of cochlear filtering. As the physiological function of the OHC model, the pressure produced by the somatic motility of the OHCs was studied. The somatic motility is induced by the transducer currents that change with the displacement of the hair bundle. The pressure produced by the OHC model can be linearly approximated by the amount of current. The proposed model is comprised of a middle ear model and a cochlear transmission‐line model, which includes a basilar membrane and lymph fluid model, a tectorial membrane model, hair bundles model, and the OHC model. The model’s parameters were set as estimates for a human obtained from animal data. In simulation results, this model could account for the IO functions of cochlear filtering obtained from both physiological and psychological experiments. These ...