Parental Adverse Childhood Experiences and Offspring Development at 2 Years of Age
Parental Adverse Childhood Experiences and Offspring Development at 2 Years of Age
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DOI：
10.1542/peds.2017-2826
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发表时间：
2018-04-01
期刊：
影响因子：
8
通讯作者：
Gillespie, Robert J.
中科院分区：
文献类型：
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作者：
Folger, Alonzo T.;Eismann, Emily A.;Gillespie, Robert J.
提示：本研究的目的是确定母亲和父亲接触不良儿童经历（ACE）有显着的关联，在24个月的年龄在郊区的儿科初级保健population.METHODS：一项回顾性队列研究进行了311母亲，儿童和122父亲，儿童二人组谁参加了一个大型的儿科初级保健实践。儿童出生于2012年10月至2014年6月，并在2个月、4个月和24个月的健康儿童访视时收集数据。多变量泊松回归与强大的误差方差模型之间的关系，自我报告的父母ACE和可疑的发育迟缓的结果，在24个月和资格早期干预service.RESULTS：对于每一个额外的母亲ACE，有一个可疑的发育迟缓的风险增加18%（相对风险：1.18，95%置信区间：1.08-1.29）。在父亲ACE中观察到类似的趋势（相对风险：1.34，95%置信区间：1.07-1.67）。三次或以上母体ACE（与
OBJECTIVES:The study objective was to determine if maternal and paternal exposure to adverse childhood experiences (ACEs) have a significant association with negative offspring development at 24 months of age in a suburban pediatric primary care population.METHODS:A retrospective cohort study was conducted of 311 mother-child and 122 father-child dyads who attended a large pediatric primary care practice. Children were born from October 2012 to June 2014, and data were collected at the 2-, 4-, and 24-month well-child visits. Multivariable Poisson regression with robust error variance was used to model the relationship between self-reported parental ACEs and the outcomes of suspected developmental delay at 24 months and eligibility for early intervention services.RESULTS:For each additional maternal ACE, there was an 18% increase in the risk for a suspected developmental delay (relative risk: 1.18, 95% confidence interval: 1.08-1.29). A similar trend was observed for paternal ACEs (relative risk: 1.34, 95% confidence interval: 1.07-1.67). Three or more maternal ACEs (versus