The Role of Metabolism in Hormonal Control of Sexual Behavior

The Role of Metabolism in Hormonal Control of Sexual Behavior
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新陈代谢在性行为激素控制中的作用

DOI：
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发表时间：
1985
期刊：
影响因子：
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通讯作者：
W. Luttge
W. Luttge
中科院分区：
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文献类型：
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作者：
R. E. Whalen;P. Yahr;W. Luttge

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1970年，Baulieu发表了一篇题为《激素代谢物的作用：内分泌学的新概念》的论文。Baulieu提出的新概念是，内分泌腺的分泌只有在细胞内代谢成活性物质后才能发挥其生物学作用。具体地说，鲍利乌认为，睾酮(T)通过局部代谢二氢睾酮(DHT)和3-二氢睾酮(3-α，5-α-androstandiol，缩写为Adiol；本章中提到的大多数类固醇和药物的化学名称、琐碎名称和缩写)来维持靶组织(如前列腺)的生长和分泌。
In 1970, Baulieu published a paper entitled “The Action of Hormone Metabolites: A New Concept in Endocrinology.” The new concept advanced by Baulieu was that the secretions of endocrine glands may exert their biological actions only after intracellular metabolism to active agents. Specifically, Baulieu suggested that testosterone (T) maintains growth and secretion of target tissues (e.g., the prostate) by local metabolism to dihydrotestosterone (DHT) and 3α, 5α-androstanediol (abbreviated Adiol; the chemical names, trivial names, and abbreviations of most of the steroids and drugs referred to in this chapter are given in Table 1).