Treatment of hyperthyroidism with iodine-131.
Treatment of hyperthyroidism with iodine-131.
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用碘 131 治疗甲状腺机能亢进症。
DOI：
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发表时间：
1982
期刊：
影响因子：
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通讯作者：
M. A. Shahid
中科院分区：
文献类型：
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作者：
S. Asghar;Mumtaz;M. A. Shahid
本文对1963~1972年10年间402例甲状腺功能亢进症患者进行了放射性碘治疗的回顾性研究。按年龄(2)性别(3)腺体大小(4)甲状腺类型(弥漫性结节)(5)眼征(6)剂量和(7)总剂量1-13 1分型。治疗的一般年龄为30~60岁，平均(±1S.D.)42.7±8.6。女性占73%，男性占27%。女性患者最常见的年龄组为31~40岁，男性患者最常见的年龄组为41~50岁。最终结果是甲状腺功能正常、甲状腺功能减退和甲状腺功能亢进。约6%的患者出现永久性甲状腺功能减退，极少数患者在甲亢时停止治疗，其余患者恢复正常。治疗后甲亢相关眼部症状缓解率为64.2%，未缓解率为31.3%，加重为4.5%(JPMA 32：29,1982)。
A retrospective study of radiolodine therapy for thyrotoxicosis was done in 402 patients over a period of 10 years from 1963 to 1972. The patients were classified as follows: (1) Age (2) Sex (3) Size of the gland estimated by physical exmination (4) Type of goitre (diffuse, nodular) (5) Ocular signs (6) Number of doses and (7) Total dose of 1-13 1 administered. The usual age for the treatment was 30 to 60 years with a mean (±1 s.d.) of 42.7±8.6. Female patients were 73% and male 27%. The most common age group for female patients was from 31 to 40 years and for males from 41 to 50 years. The end results were euthyroid, hypothyroid and hyperthyroid states. About 6% of the cases developed permanent hypothyroidism, very few cases stopped treatment while they were still hyperthyroid and rest of them became euthyroid. The ocular symptoms associated with hyperthyroidism were relieved in 64.2%, not relieved in 31.3% and aggravated in 4.5% after 1-131 treatment (JPMA 32:29, 1982).