An Arterial Spin Labeling MRI Perfusion Study of Migraine without Aura Attacks.
An Arterial Spin Labeling MRI Perfusion Study of Migraine without Aura Attacks.
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DOI：
10.3389/fneur.2017.00280
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发表时间：
2017
影响因子：
3.4
通讯作者：
Martins IP
中科院分区：
文献类型：
--
作者：
Gil-Gouveia R;Pinto J;Figueiredo P;Vilela PF;Martins IP
无先兆偏头痛发作期间的脑灌注研究结果不一致。动脉自旋标记磁共振成像，一种非侵入性定量灌注技术，被用来前瞻性研究自发性未经治疗的偏头痛没有先兆发作和头痛的自由期。图像分析采用FSL和MATLAB软件;分组分析采用置换法分析不同疗程间的灌注差异。13名妇女（35.7岁）进行了扫描，在攻击的平均强度为6.8（0-10视觉模拟量表）和16小时的持续时间。在比较偏头痛和无偏头痛治疗时，没有发现整体或区域灌注差异。我们的研究结果表明，无先兆偏头痛发作的疼痛阶段与脑灌注异常无关。
Studies of brain perfusion during migraine without aura attacks have inconsistent results. Arterial spin labeling MRI, a non-invasive quantitative perfusion technique, was used to prospectively study a spontaneous untreated migraine without aura attack and a headache-free period. Image analysis used FSL and MATLAB software; Group analysis used permutation methods for perfusion differences between sessions. Thirteen women (age 35.7) were scanned during an attack of an average intensity of 6.8 (on 0–10 Visual Analog Scale) and 16 h duration. No global or regional perfusion differences were identified when comparing migraine and migraine-free sessions. Our findings suggest that the painful phase of migraine without aura attacks is not associated with brain perfusion abnormalities.