GSTM1 polymorphism and oral squamous cell carcinoma
GSTM1 polymorphism and oral squamous cell carcinoma
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DOI：
10.1016/s1368-8375(03)00132-5
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发表时间：
2004-01-01
期刊：
影响因子：
4.8
通讯作者：
Gomez, RS
中科院分区：
文献类型：
--
作者：
Drummond, SN;De Marco, L;Gomez, RS
我们调查了70例巴西口腔鳞状细胞癌（OSCC）患者和82例年龄性别匹配的对照组中GSTM 1基因型的频率。GSTM 1基因型通过PCR方法进行了研究。口腔鳞癌患者与口腔癌阴性患者配对的频率。GSTM 1阳性率为70.5%，对照组阳性率为48.5%，差异有统计学意义（OR=2.53，95%CI =1.22-5.24，P
We investigated the frequency of the GSTM1 genotypes in 70 Brazilian patients with oral squamous cell carcinoma (OSCC) and 82 age-sex matched controls. The GSTM1 genotypes were studied by PCR-based methods. The frequency of mate patients with OSCC and null. for the GSTM1 (70.5%) was statistically different from the mate patients from the control group (48.5%) (Odds Ratio, OR=2.53, 95% Cl=1.22-5.24, P