MEG/EEG sources of the 170-ms response to faces are co-localized in the fusiform gyrus
MEG/EEG sources of the 170-ms response to faces are co-localized in the fusiform gyrus
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DOI：
10.1016/j.neuroimage.2007.01.034
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发表时间：
2007-05-01
期刊：
影响因子：
5.7
通讯作者：
Lueschow, Andreas
中科院分区：
文献类型：
--
作者：
Deffke, Iris;Sander, Tilmann;Lueschow, Andreas
170ms的电生理加工阶段(脑电中的N170，脑磁图中的M170)被认为是人脸加工中的一个重要计算步骤。因此，它的网络来源已经在几项研究中建立了模型。目前的研究旨在明确N170和M170背后的偶极源的关系。在呈现陌生面孔时，同时测量全头脑电和脑磁图。对定位前的数据进行独立成分分析(ICA)。然后用一对偶极子模拟N170和M170，该偶极子在中线上对称排列的四壳椭圆(EEG)/均匀球(MEG)中。偶极子位置被投影到单独的结构磁共振脑图像上。脑电图显示偶极子位于梭状回的比例为10/11，脑磁图的比例为7/11。在6个个体中，N170和M170共定位于梭形回。ICA将一些单一受试者的偶极子从小脑上移到梭形回，主要是由于心脏活动的移除。该组的平均偶极子位置也在后部梭形回，EEG和MEG之间没有显著差异。3个月后，重复测量了这一结果。(C)2007 Elsevier Inc.保留所有权利。
The 170-ms electrophysiological processing stage (N170 in EEG, M170 in MEG) is considered an important computational step in face processing. Hence its neturonal sources have been modelled in several studies. The current study aimed to specify the relation of the dipolar sources underlying N170 and M170. Whole head EEG and MEG were measured simultaneously during the presentation of unfamiliar faces. An Independent Component Analysis (ICA) was applied to the data prior to localization. N170 and M170 were then modelled with a pair of dipoles in a four-shell ellipse (EEG)/homogeneous sphere (MEG) arranged symmetrically across midline. The dipole locations were projected onto the individual structural MR brain images. Dipoles were localized in fusiform gyri in ten out of eleven individuals for EEG and in seven out of eleven for MEG. N170 and M170 were co-localized in the fusiform gyros in six individuals. The ICA shifted some of the single-subject dipoles up from cerebellum to fusiform gyros mainly due to the removal of cardiac activity. The group mean dipole locations were also found in posterior fusiform gyri, and did not differ significantly between EEG and MEG. The result was replicated in a repeated measurement 3 months later. (c) 2007 Elsevier Inc. All rights reserved.